TGF-β Pathways in Aging and Immunity: Lessons from

Overview

Journal Front Genet

Date 2023 Sep 21

PMID 37732316

Authors

Katerina K Yamamoto

Cathy Savage-Dunn

Affiliations

Soon will be listed here.

Abstract

The Transforming Growth Factor-β (TGF-β) superfamily of signaling molecules plays critical roles in development, differentiation, homeostasis, and disease. Due to the conservation of these ligands and their signaling pathways, genetic studies in invertebrate systems including the nematode have been instrumental in identifying signaling mechanisms. is also a premier organism for research in longevity and healthy aging. Here we summarize current knowledge on the roles of TGF-β signaling in aging and immunity.

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