Thrombotic Microangiopathy After Traumatic Brain Injury: A Case Report and Review of the Literature

Overview

Journal Clin Case Rep

Date 2023 Sep 11

PMID 37692157

Authors

Xavier Van Meerbeeck

Leen Janssen

Rowena Vleut

Philip Verdonck

Alain Gadisseur

Rudi De Paep

Walter Verbrugghe

Philippe Jorens

Affiliations

Soon will be listed here.

Abstract

Key Clinical Message: This case report supports that trauma can rarely cause thrombotic microangiopathy (TMA). Early recognition is important due to a high mortality of untreated TMA, but diagnosis can be delayed by attributing lab abnormalities as due to blood loss.

Abstract: Major trauma can provoke coagulopathy, ranging from hypo- to hypercoagulation. Thrombotic microangiopathy (TMA), characterized by hemolytic anemia, renal failure, thrombocytopenia, and intravascular hemolysis, results in bleeding tendency but also microvascular thrombosis. We report a rare case of isolated traumatic brain injury leading to TMA treated with plasmapheresis.

Citing Articles

Thrombotic microangiopathy after traumatic brain injury: A case report and review of the literature.

Van Meerbeeck X, Janssen L, Vleut R, Verdonck P, Gadisseur A, Paep R Clin Case Rep. 2023; 11(9):e7838.

PMID: 37692157 PMC: 10491750. DOI: 10.1002/ccr3.7838.

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