Expression and Cilia Associated Localization of Histone Deacetylases 6 in

Overview

Journal MicroPubl Biol

Specialty Biology

Date 2023 Aug 31

PMID 37649557

Authors

Matthias Tisler

Tim Ott

Martin Blum

Axel Schweickert

Affiliations

Soon will be listed here.

Abstract

Histone deacetylases (HDACs) are key posttranslational modulators of the proteome. We show that expression of ( ) is dynamic and appears in a tissue specific manner throughout embryonic development of the frog Xenopus . Interestingly, transcripts often associate with ciliated tissues, like the left-right organizer at neurula stage or the pronephros. In the embryonic skin, Hdac6 protein localizes to the cilia base, suggesting a functional link.

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