Simultaneous Irradiation with UV-A, -B, and -C Lights Promotes Effective Decontamination of Planktonic and Sessile Bacteria: A Pilot Study

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2023 Aug 26

PMID 37629131

Authors

Andrea Bosso

Francesca Tortora

Rosanna Culurciello

Ilaria Di Nardo

Valeria Pistorio

Federica Carraturo

Andrea Colecchia

Rocco Di Girolamo

Valeria Cafaro

Eugenio Notomista

Raffaele Ingenito

Elio Pizzo

Affiliations

Soon will be listed here.

Abstract

Surfaces in highly anthropized environments are frequently contaminated by both harmless and pathogenic bacteria. Accidental contact between these contaminated surfaces and people could contribute to uncontrolled or even dangerous microbial diffusion. Among all possible solutions useful to achieve effective disinfection, ultraviolet irradiations (UV) emerge as one of the most "Green" technologies since they can inactivate microorganisms via the formation of DNA/RNA dimers, avoiding the environmental pollution associated with the use of chemical sanitizers. To date, mainly UV-C irradiation has been used for decontamination purposes, but in this study, we investigated the cytotoxic potential on contaminated surfaces of combined UV radiations spanning the UV-A, UV-B, and UV-C spectrums, obtained with an innovative UV lamp never conceived so far by analyzing its effect on a large panel of collection and environmental strains, further examining any possible adverse effects on eukaryotic cells. We found that this novel device shows a significant efficacy on different planktonic and sessile bacteria, and, in addition, it is compatible with eukaryotic skin cells for short exposure times. The collected data strongly suggest this new lamp as a useful device for fast and routine decontamination of different environments to ensure appropriate sterilization procedures.

Citing Articles

Comparative assessment of UV-C radiation and non-thermal plasma for inactivation of foodborne fungal spores suspension .

Kulisova M, Rabochova M, Lorincik J, Matatkova O, Branyik T, Hrudka J RSC Adv. 2024; 14(24):16835-16845.

PMID: 38784412 PMC: 11114098. DOI: 10.1039/d4ra01689k.

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