Emulsifiers During Gestation: The Risks of Ultra-processed Food Revealed in Mice
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
Several dietary components disrupt the control of energy balance. A new study in PLOS Biology shows that, in mice, maternal consumption of emulsifiers induces a rewiring of the hypothalamic feeding circuits and causes neuropsychological impairment in the offspring.
References
1.
Park S, Belfoul A, Rastelli M, Jang A, Monnoye M, Bae H
. Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway. JCI Insight. 2023; 8(10).
PMC: 10322686.
DOI: 10.1172/jci.insight.156397.
View
2.
Barker D, WINTER P, Osmond C, Margetts B, Simmonds S
. Weight in infancy and death from ischaemic heart disease. Lancet. 1989; 2(8663):577-80.
DOI: 10.1016/s0140-6736(89)90710-1.
View
3.
Buckley J, Kim H, Wong E, Rebholz C
. Ultra-processed food consumption and exposure to phthalates and bisphenols in the US National Health and Nutrition Examination Survey, 2013-2014. Environ Int. 2019; 131:105057.
PMC: 6728187.
DOI: 10.1016/j.envint.2019.105057.
View
4.
Mila-Guasch M, Ramirez S, Llana S, Fos-Domenech J, Dropmann L, Pozo M
. Maternal emulsifier consumption programs offspring metabolic and neuropsychological health in mice. PLoS Biol. 2023; 21(8):e3002171.
PMC: 10449393.
DOI: 10.1371/journal.pbio.3002171.
View
5.
Marraudino M, Ponti G, Moussu C, Farinetti A, Macchi E, Accornero P
. Early Postnatal Genistein Administration Affects Mice Metabolism and Reproduction in a Sexually Dimorphic Way. Metabolites. 2021; 11(7).
PMC: 8303179.
DOI: 10.3390/metabo11070449.
View