Global Prevalence of Infection Among Individuals with Obesity: A Protocol for a Systematic Review and Meta-analysis

Overview

Journal Health Sci Rep

Specialty General Medicine

Date 2023 Aug 24

PMID 37614286

Authors

Alireza Sadeghi

Niloofar Dehdari Ebrahimi

Affiliations

Soon will be listed here.

Abstract

Background And Aims: Modern populations are prone to obesity, as sedentary lifestyles prevail globally. Previous research has shown that obesity and are mutually associated. However, the global prevalence of among individuals with obesity is not yet determined.

Methods: A comprehensive search will be conducted in PubMed, Scopus, and Web of Science online databases for studies that have reported the prevalence of infection among individuals with obesity. Cross-sectional, case-control, and cohort studies will be included if reported sufficient data. Records screening, data extraction, and quality assessment will be done by independent reviewers. Joanna Bridge Institute checklist for prevalence studies will be used to appraise the included studies. Prevalence will be pooled using random effect models. Heterogeneity will be quantified by and value. Subgroup analyses and meta-regression will be utilized to address the sources of residual between-study heterogeneity.

Discussion: Understanding the regional and global occurrence of infection in individuals with obesity can provide valuable insights for health policymakers and clinicians to devise proficient diagnostic and eradication strategies, thereby enhancing postoperative outcomes for patients undergoing bariatric surgery. The study's strength will lie in not being restricted to language and time of publication, comprehensive investigation of regional and pre- and posteradication estimates, and the effects of time trends and sociodemographic indices on prevalence. However, potential heterogeneity in methodologies used across prevalence studies could affect the interpretation of the results. Additionally, the study relies on previously published studies, limiting data quality and completeness.

Citing Articles

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Global prevalence of infection among individuals with obesity: A protocol for a systematic review and meta-analysis.

Sadeghi A, Dehdari Ebrahimi N Health Sci Rep. 2023; 6(8):e1505.

PMID: 37614286 PMC: 10442524. DOI: 10.1002/hsr2.1505.

References

Kyriazanos I, Sfiniadakis I, Gizaris V, Hountis P, Hatziveis K, Dafnopoulou A . The incidence of Helicobacter pylori infection is not increased among obese young individuals in Greece. J Clin Gastroenterol. 2002; 34(5):541-6. DOI: 10.1097/00004836-200205000-00012. View

Arslan E, Atilgan H, Yavasoglu I . The prevalence of Helicobacter pylori in obese subjects. Eur J Intern Med. 2009; 20(7):695-7. DOI: 10.1016/j.ejim.2009.07.013. View

Hunter J, Saratzis A, Sutton A, Boucher R, Sayers R, Bown M . In meta-analyses of proportion studies, funnel plots were found to be an inaccurate method of assessing publication bias. J Clin Epidemiol. 2014; 67(8):897-903. DOI: 10.1016/j.jclinepi.2014.03.003. View

Cardos I, Zaha D, Sindhu R, Cavalu S . Revisiting Therapeutic Strategies for Treatment in the Context of Antibiotic Resistance: Focus on Alternative and Complementary Therapies. Molecules. 2021; 26(19). PMC: 8512130. DOI: 10.3390/molecules26196078. View

Sadeghi A, Dehdari Ebrahimi N . Global prevalence of infection among individuals with obesity: A protocol for a systematic review and meta-analysis. Health Sci Rep. 2023; 6(8):e1505. PMC: 10442524. DOI: 10.1002/hsr2.1505. View

Pintar T, Kaliterna N, Carli T . The need for a patient-tailored Helicobacter pylori eradication protocol prior to bariatric surgery. J Int Med Res. 2018; 46(7):2696-2707. PMC: 6124286. DOI: 10.1177/0300060518769543. View

Kuper M, Kratt T, Kramer K, Zdichavsky M, Schneider J, Glatzle J . Effort, safety, and findings of routine preoperative endoscopic evaluation of morbidly obese patients undergoing bariatric surgery. Surg Endosc. 2010; 24(8):1996-2001. DOI: 10.1007/s00464-010-0893-5. View

Smolka A, Backert S . How Helicobacter pylori infection controls gastric acid secretion. J Gastroenterol. 2012; 47(6):609-18. DOI: 10.1007/s00535-012-0592-1. View

Hooi J, Lai W, Ng W, Suen M, Underwood F, Tanyingoh D . Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis. Gastroenterology. 2017; 153(2):420-429. DOI: 10.1053/j.gastro.2017.04.022. View

10.

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A . Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016; 5(1):210. PMC: 5139140. DOI: 10.1186/s13643-016-0384-4. View

11.

Kim S, Ruiz V, Carroll J, Moss S . Helicobacter pylori in the pathogenesis of gastric cancer and gastric lymphoma. Cancer Lett. 2010; 305(2):228-38. PMC: 2980557. DOI: 10.1016/j.canlet.2010.07.014. View

12.

Carabotti M, DErcole C, Iossa A, Corazziari E, Silecchia G, Severi C . Helicobacter pylori infection in obesity and its clinical outcome after bariatric surgery. World J Gastroenterol. 2014; 20(3):647-53. PMC: 3921474. DOI: 10.3748/wjg.v20.i3.647. View

13.

Al-Akwaa A . Prevalence of Helicobacter pylori infection in a group of morbidly obese Saudi patients undergoing bariatric surgery: a preliminary report. Saudi J Gastroenterol. 2010; 16(4):264-7. PMC: 2995094. DOI: 10.4103/1319-3767.70610. View

14.

DiBaise J, Zhang H, Crowell M, Krajmalnik-Brown R, Decker G, Rittmann B . Gut microbiota and its possible relationship with obesity. Mayo Clin Proc. 2008; 83(4):460-9. DOI: 10.4065/83.4.460. View

15.

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009; 151(4):264-9, W64. DOI: 10.7326/0003-4819-151-4-200908180-00135. View

16.

Valadares E, Gestic M, Utrini M, Chaim F, Chaim E, Cazzo E . PRE-OPERATIVE SCREENING OF HELICOBACTER PYLORI IN BARIATRIC PATIENTS: IS HISTOPATHOLOGICAL ANALYSIS NECESSARY?. Arq Gastroenterol. 2022; 59(2):275-280. DOI: 10.1590/S0004-2803.202202000-49. View

17.

Wu M, Lee W, Wang H, Huang S, Lin J . A case-control study of association of Helicobacter pylori infection with morbid obesity in Taiwan. Arch Intern Med. 2005; 165(13):1552-5. DOI: 10.1001/archinte.165.13.1552. View

18.

Kassie A, Abate B, Kassaw M . Prevalence of overweight/obesity among the adult population in Ethiopia: a systematic review and meta-analysis. BMJ Open. 2020; 10(8):e039200. PMC: 7412611. DOI: 10.1136/bmjopen-2020-039200. View

19.

Kuipers E . Helicobacter pylori and the risk and management of associated diseases: gastritis, ulcer disease, atrophic gastritis and gastric cancer. Aliment Pharmacol Ther. 1997; 11 Suppl 1:71-88. DOI: 10.1046/j.1365-2036.11.s1.5.x. View

20.

Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M . Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015; 4:1. PMC: 4320440. DOI: 10.1186/2046-4053-4-1. View