Immune-Ageing Evaluation of Peripheral T and NK Lymphocyte Subsets in Chinese Healthy Adults

Overview

Journal Phenomics

Publisher Springer

Date 2023 Aug 17

PMID 37589027

Authors

Zhenghu Jia

Zhiyao Ren

Dongmei Ye

Jiawei Li

Yan Xu

Hui Liu

Ziyu Meng

Chengmao Yang

Xiaqi Chen

Xinru Mao

Xueli Luo

Zhe Yang

Lina Ma

Anyi Deng

Yafang Li

Bingyu Han

Junping Wei

Chongcheng Huang

Zheng Xiang

Guobing Chen

Peiling Li

Juan Ouyang

Peisong Chen

Oscar Junhong Luo

Yifang Gao

Zhinan Yin

Affiliations

Soon will be listed here.

Abstract

Supplementary Information: The online version contains supplementary material available at 10.1007/s43657-023-00106-0.

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References

Huang Z, Chen B, Liu X, Li H, Xie L, Gao Y . Effects of sex and aging on the immune cell landscape as assessed by single-cell transcriptomic analysis. Proc Natl Acad Sci U S A. 2021; 118(33). PMC: 8379935. DOI: 10.1073/pnas.2023216118. View

Joosten S, Ottenhoff T . Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination. Hum Immunol. 2008; 69(11):760-70. DOI: 10.1016/j.humimm.2008.07.017. View

Minami R, Yamamoto M, Takahama S, Miyamura T, Watanabe H, Suematsu E . RCAS1 induced by HIV-Tat is involved in the apoptosis of HIV-1 infected and uninfected CD4+ T cells. Cell Immunol. 2007; 243(1):41-7. DOI: 10.1016/j.cellimm.2006.11.003. View

Frasca D, Pallikkuth S, Pahwa S . Effects of Aging on Metabolic Characteristics of Human B Cells. J Acquir Immune Defic Syndr. 2022; 89(Suppl 1):S23-S28. PMC: 8751285. DOI: 10.1097/QAI.0000000000002860. View

Xia Y, Liu A, Li W, Liu Y, Zhang G, Ye S . Reference range of naïve T and T memory lymphocyte subsets in peripheral blood of healthy adult. Clin Exp Immunol. 2022; 207(2):208-217. PMC: 8982966. DOI: 10.1093/cei/uxab038. View

Carrasco E, Gomez de Las Heras M, Gabande-Rodriguez E, Desdin-Mico G, Aranda J, Mittelbrunn M . The role of T cells in age-related diseases. Nat Rev Immunol. 2021; 22(2):97-111. DOI: 10.1038/s41577-021-00557-4. View

Luo O, Lei W, Zhu G, Ren Z, Xu Y, Xiao C . Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty. Nat Aging. 2023; 2(4):348-364. DOI: 10.1038/s43587-022-00198-9. View

Fragiadakis G, Bjornson-Hooper Z, Madhireddy D, Sachs K, Chen H, McIlwain D . Variation of Immune Cell Responses in Humans Reveals Sex-Specific Coordinated Signaling Across Cell Types. Front Immunol. 2022; 13:867016. PMC: 8995898. DOI: 10.3389/fimmu.2022.867016. View

Ribot J, Lopes N, Silva-Santos B . γδ T cells in tissue physiology and surveillance. Nat Rev Immunol. 2020; 21(4):221-232. DOI: 10.1038/s41577-020-00452-4. View

10.

Dizaji Asl K, Velaei K, Rafat A, Nasrabadi H, Movassaghpour A, Mahdavi M . The role of KIR positive NK cells in diseases and its importance in clinical intervention. Int Immunopharmacol. 2021; 92:107361. DOI: 10.1016/j.intimp.2020.107361. View

11.

Miles D, van der Sande M, Jeffries D, Kaye S, Ismaili J, Ojuola O . Cytomegalovirus infection in Gambian infants leads to profound CD8 T-cell differentiation. J Virol. 2007; 81(11):5766-76. PMC: 1900274. DOI: 10.1128/JVI.00052-07. View

12.

Mogilenko D, Shchukina I, Artyomov M . Immune ageing at single-cell resolution. Nat Rev Immunol. 2021; 22(8):484-498. PMC: 8609266. DOI: 10.1038/s41577-021-00646-4. View

13.

Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A . Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors. Nat Immunol. 2018; 19(3):302-314. DOI: 10.1038/s41590-018-0049-7. View

14.

Krzych U, STRAUSSER H, Bressler J, Goldstein A . Effects of sex hormones on some T and B cell functions, evidenced by differential immune expression between male and female mice and cyclic pattern of immune responsiveness during the estrous cycle in female mice. Am J Reprod Immunol (1980). 1981; 1(2):73-7. DOI: 10.1111/j.1600-0897.1981.tb00020.x. View

15.

Caruso C, Ligotti M, Accardi G, Aiello A, Candore G . An immunologist's guide to immunosenescence and its treatment. Expert Rev Clin Immunol. 2022; 18(9):961-981. DOI: 10.1080/1744666X.2022.2106217. View

16.

Goodier M, White M, Darboe A, Nielsen C, Goncalves A, Bottomley C . Rapid NK cell differentiation in a population with near-universal human cytomegalovirus infection is attenuated by NKG2C deletions. Blood. 2014; 124(14):2213-22. PMC: 4206953. DOI: 10.1182/blood-2014-05-576124. View

17.

Qin L, Jing X, Qiu Z, Cao W, Jiao Y, Routy J . Aging of immune system: Immune signature from peripheral blood lymphocyte subsets in 1068 healthy adults. Aging (Albany NY). 2016; 8(5):848-59. PMC: 4931839. DOI: 10.18632/aging.100894. View

18.

Valdiglesias V, Sanchez-Flores M, Maseda A, Marcos-Perez D, Millan-Calenti J, Pasaro E . Lymphocyte Subsets in a Population of Nonfrail Elderly Individuals. J Toxicol Environ Health A. 2015; 78(13-14):790-804. DOI: 10.1080/15287394.2015.1051170. View

19.

Nie C, Li Y, Li R, Yan Y, Zhang D, Li T . Distinct biological ages of organs and systems identified from a multi-omics study. Cell Rep. 2022; 38(10):110459. DOI: 10.1016/j.celrep.2022.110459. View

20.

Ligotti M, Aiello A, Accardi G, Aprile S, Bonura F, Bulati M . Analysis of T and NK cell subsets in the Sicilian population from young to supercentenarian: The role of age and gender. Clin Exp Immunol. 2021; 205(2):198-212. PMC: 8274165. DOI: 10.1111/cei.13606. View