Epigenetic Regulation of Nuclear Processes in Fungal Plant Pathogens

Overview

Journal PLoS Pathog

Specialty Microbiology

Date 2023 Aug 3

PMID 37535497

Authors

H Martin Kramer

David E Cook

Michael F Seidl

Bart P H J Thomma

Affiliations

Soon will be listed here.

Abstract

Through the association of protein complexes to DNA, the eukaryotic nuclear genome is broadly organized into open euchromatin that is accessible for enzymes acting on DNA and condensed heterochromatin that is inaccessible. Chemical and physical alterations to chromatin may impact its organization and functionality and are therefore important regulators of nuclear processes. Studies in various fungal plant pathogens have uncovered an association between chromatin organization and expression of in planta-induced genes that are important for pathogenicity. This review discusses chromatin-based regulation mechanisms as determined in the fungal plant pathogen Verticillium dahliae and relates the importance of epigenetic transcriptional regulation and other nuclear processes more broadly in fungal plant pathogens.

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