The Effects of a Physical Exercise Program in Chinese Kidney Transplant Recipients: a Prospective Randomised Controlled Trial

Overview

Journal Clin Kidney J

Publisher Oxford University Press

Specialty Nephrology

Date 2023 Aug 2

PMID 37529646

Authors

Pengpeng Zhang

Shan Liu

Xiao Zhu

Huan Liu

Le Zeng

Jin Yan

Jia Liu

Affiliations

Soon will be listed here.

Abstract

Background: Kidney transplant has become the preferred therapy for end-stage renal disease. However, kidney transplant recipients (KTRs) still face several challenges, such as physical inactivity. The purpose of this study was to explore the effects of a nurse-led physical exercise program in Chinese KTRs.

Methods: A total of 106 participants were enrolled from the Third Xiangya Hospital of Central South University between July 2021 and June 2022 and randomly assigned to the control or intervention groups. Participants in the control group were provided with routine nursing care and participants in the intervention group received a nurse-led rigorous physical exercise program that was divided into two stages: the pre-discharge stage and the post-discharge stage. The pre-discharge stage included the non-ambulatory and ambulatory stages. The Chinese traditional exercise Baduanjin was incorporated into the physical exercise during the ambulatory stage. The post-discharge stage continued the same exercise as the ambulatory stage at home. After 3 months of intervention, both groups received the same follow-up for 3 months. The primary and secondary outcomes of all participants were collected. The data were analysed with repeated measures analysis of variance to examine the effectiveness of the intervention.

Results: Compared with the control group, the intervention group had less fatigue and more motivation to be active in primary outcomes. Moreover, patients in the intervention group had a higher phase angle, a longer 6-minute walk distance, more 30-second chair stand times and decreased anxiety and depression levels in secondary outcomes. No adverse events were observed during the intervention. There were no significant differences in all dimensions of the quality-of-life questionnaire between the intervention and the control group.

Conclusion: Chinese KTRs could benefit from the nurse-led physical exercise program post-operatively.

Trial Registration: ChiCTR2100048755.

Citing Articles

Association between physical activity and immunosuppressive medication adherence among renal transplant recipients: a case-control study.

Zhang P, Fan X, Xiang L, Zhu X, Liu D, Liu J BMJ Open. 2024; 14(10):e080695.

PMID: 39477281 PMC: 11529692. DOI: 10.1136/bmjopen-2023-080695.

Tailored exercise with telehealth monitoring improves adherence and global health in kidney transplant recipients.

Vecchiato M, Duregon F, Zanardo E, Baioccato V, Quinto G, Livio A Front Sports Act Living. 2024; 6:1436742.

PMID: 39346494 PMC: 11438482. DOI: 10.3389/fspor.2024.1436742.

Systematic review and meta-analysis of the efficacy of exercise intervention in kidney transplant recipients.

Zhang D, Yu L, Xia B, Zhang X, Liang P, Hu X World J Urol. 2023; 41(12):3449-3469.

PMID: 37882807 DOI: 10.1007/s00345-023-04673-9.

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