() Infection-Associated Anemia in the Asir Region, Saudi Arabia

(ubiquitous) and anemia together represent one of the growing health concerns globally. Gastroduodenal sequelae of infection are distinguished; however, for the infection and its implication in the development of anemia, iron has a significant health impact. We aimed to evaluate infection-associated anemia by employing a logistic regression analysis model. A retrospective (case-control) study design-based assessment of the associated-anemia. The study area was geo-referenced by QGIS/QuickMapServies. Descriptive and inferential statistical analyses were accomplished using the R-base-R-studio (v-4.0.2)-tidyverse. A -value < 0.05 was the statistical significance cut-off value. A ggplot2 package was used for data representation and visualization. Mean ± SD age, Hb, MCV, ferritin, and RBC for overall study participants were measured to be 44.0 ± 13.58, 13.84 ± 2.49, 83.02 ± 8.31, 59.42 ± 68.37, and 5.14 ± 0.75, respectively. Decreased levels of Hb (infected vs. uninfected: 13.26 ± 2.92 vs. 14.42 ± 1.75, < 0.001) ferritin (infected vs. uninfected: 48.11 ± 63.75 vs. 71.17 ± 71.14, < 0.001), and MCV (infected vs. uninfected: 81.29 ± 9.13 vs. and 84.82 ± 6.93, < 0.05) were measured to be associated with infection when compared with uninfected control group. Moreover, the magnitude (prevalence) of anemia (infected vs. uninfected: 78% vs. 21%, < 0.001), iron deficiency anemia (IDA) (infected vs. uninfected: 63.3% vs. 36.6%, < 0.001), and microcytic anemia (infected vs. uninfected: 71.6% vs. 46.1%, < 0.001) were significantly different among the -infected participants. The higher likelihood of developing anemia (AOR; 4.98, 95% CI; 3.089-8.308, < 0.001), IDA (AOR; 3.061, 95% CI; 2.135-4.416, < 0.001), and microcytic anemia (AOR; 3.289, 95% CI; 2.213-4.949, < 0.001) by 398%, 206.1%, and 229%, respectively, was associated with -infected. We recommend the regular monitoring of hematological parameters and eradication of infection to minimize the extra-gastric health consequences of infection.