Sero- and Feco-Prevalence of Infection and Its Associated Risk Factors Among Adult Dyspeptic Patients Visiting the Outpatient Department of Adet Primary Hospital, Yilmana Densa District, Northwest Ethiopia

Overview

Journal Can J Infect Dis Med Microbiol

Publisher Wiley

Date 2023 Jul 26

PMID 37492856

Authors

Zebasil Mnichil

Endalkachew Nibret

Daniel Mekonnen

Maritu Demelash

Affiliations

Soon will be listed here.

Abstract

Background: Most gastric cancers in the world are attributed to () infections. The prevalence of infection is influenced by socioeconomic status, hygiene, and lifestyle of the population. This study aimed to assess sero- and feco-prevalence of infections and its associated risk factors among adult dyspeptic patients visiting the outpatient department of Adet Primary Hospital, Yilmana Densa District, northwest Ethiopia.

Methods: A hospital-based cross-sectional study was conducted from February 10, 2022 to April 10, 2022. The study participants were selected using a systematic random sampling technique. The data were collected by pretested questionnaires. Blood and stool specimens were collected from each patient for antibody and antigen tests, respectively. The data were analyzed using Statistical Package for Social Science (SPSS) version 26.0. A logistic regression model was used to assess the strength of association between positivity and risk factors.

Results: The sero- and feco-prevalence of infection was 62% and 51.1%, respectively. In those patients who had a positive result with either the antibody (Ab) or antigen (Ag) test, rural residence (AOR = 5.55; 95% CI: 2.34-13.14; < 0.001), alcohol consumption (AOR = 12.34; 95% CI: 2.29-66.51; =0.003), having no awareness about transmission (AOR = 4.76; 95% CI: 1.86-12.15; =0.001), using pond/river as a source of drinking water (AOR = 5.22; 95% CI: 1.91-14.27; =0.001), and open field defecation (AOR = 4.19; 95% CI: 1.67-10.52; =0.002) were the explanatory risk factors significantly associated with infection.

Conclusion: This study showed that the prevalence of infection was very high. Most cases of gastric cancers are ascribed to infection. Therefore, education should be given to communities so as to increase their awareness of the infection and the associated major explanatory risk factors identified in the present study.

Citing Articles

Prevalence of Helicobacter pylori infection and effectiveness of first-line triple eradication therapy among dyspeptic patients at hospitals in Hawassa City, Ethiopia: a cross-sectional follow-up study.

Fekadu S, Kibru S, Tesfaye S, Egeno T, Tamiso A, Engiso H Gut Pathog. 2024; 16(1):23.

PMID: 38678267 PMC: 11056052. DOI: 10.1186/s13099-024-00618-8.

Sero- and Feco-Prevalence of Infection and Its Associated Risk Factors among Adult Dyspeptic Patients Visiting the Outpatient Department of Adet Primary Hospital, Yilmana Densa District, Northwest Ethiopia.

Mnichil Z, Nibret E, Mekonnen D, Demelash M Can J Infect Dis Med Microbiol. 2023; 2023:2305681.

PMID: 37492856 PMC: 10365919. DOI: 10.1155/2023/2305681.

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