» Articles » PMID: 37492702

Overactivation of Histone Deacetylases and EZH2 in Wilms Tumorigenesis

Overview
Journal Genes Dis
Date 2023 Jul 26
PMID 37492702
Authors
Affiliations
Soon will be listed here.
Citing Articles

Modeling high-risk Wilms tumors enables the discovery of therapeutic vulnerability.

Ma G, Gao A, Chen J, Liu P, Sarda R, Gulliver J Cell Rep Med. 2024; 5(10):101770.

PMID: 39368485 PMC: 11513831. DOI: 10.1016/j.xcrm.2024.101770.

References
1.
Liu H, Chen S, Yao X, Li Y, Chen C, Liu J . Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018; 145(10). PMC: 6001373. DOI: 10.1242/dev.153619. View

2.
Presser Aiden A, Rivera M, Rheinbay E, Ku M, Coffman E, Truong T . Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. Cell Stem Cell. 2010; 6(6):591-602. PMC: 2897075. DOI: 10.1016/j.stem.2010.03.016. View

3.
OBrien L, Guo Q, Lee Y, Tran T, Benazet J, Whitney P . Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. Development. 2016; 143(4):595-608. PMC: 4760318. DOI: 10.1242/dev.127175. View

4.
Liu H, Hilliard S, Kelly E, Chen C, Saifudeen Z, El-Dahr S . The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice. J Biol Chem. 2020; 295(33):11542-11558. PMC: 7450110. DOI: 10.1074/jbc.RA120.013348. View

5.
Walz A, Ooms A, Gadd S, Gerhard D, Smith M, Guidry Auvil J . Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors. Cancer Cell. 2015; 27(2):286-97. PMC: 4800737. DOI: 10.1016/j.ccell.2015.01.003. View