Ocular Complications of Antineoplastic Therapies
Overview
Affiliations
Ocular complications of antineoplastic agents can have a profound effect on the quality of life of cancer patients. New oncologic treatments like monoclonal antibodies, immunotherapies, antibody-drug conjugates, checkpoint inhibitors and growth factor receptors have resulted in increased ocular complications. These ocular complications differs in respect to distinct mechanisms of actions and lead to significant challenges in the management of cancer patients. In this review, we reviewed literature, clinical studies and cases detailing ocular complications due to administration of antineoplastic agents and emphasized the need for communication between oncologists and ophthalmologists toward early detection and management of ocular complications.
Management of severe capecitabine-induced corneal toxicity.
Heyvaert M, Denys H, Van Dorpe J, Roels D Am J Ophthalmol Case Rep. 2024; 36:102174.
PMID: 39319200 PMC: 11421284. DOI: 10.1016/j.ajoc.2024.102174.
Case report: a cataract induced by bleomycin in a patient with testicular cancer.
Zhang W, Ji Y, Sun Y, Zhi K, Yang H, Zhang M Front Pharmacol. 2024; 15:1339662.
PMID: 38966544 PMC: 11222336. DOI: 10.3389/fphar.2024.1339662.
[Staging and systemic treatment of ocular and periocular metastases].
Dorfel D, Babst N, Heindl L, Kakkassery V, Muller M Ophthalmologie. 2024; 121(5):374-381.
PMID: 38683363 DOI: 10.1007/s00347-024-02034-4.
Ocular Surface Side Effects of Novel Anticancer Drugs.
Vitiello L, Lixi F, Coco G, Giannaccare G Cancers (Basel). 2024; 16(2).
PMID: 38254833 PMC: 10814578. DOI: 10.3390/cancers16020344.