The Impact of the COVID-19 Pandemic on the Diagnosis and Treatment of Skin Cancers, a Mini Review

Overview

Journal Cancer Rep (Hoboken)

Specialty Oncology

Date 2023 Jul 12

PMID 37434543

Authors

Zeinab Aryanian

Kamran Balighi

Azadeh Goodarzi

Ali Sadeghi Nia

Zeinab Mohseni Afshar

Parvaneh Hatami

Affiliations

Soon will be listed here.

Abstract

Background: The SARS-Cov-2 pandemic has caused dermatologists around the world to adapt their practice in the aim of protecting patients with special clinical conditions such as those having skin cancers or premalignant conditions and some diagnostic or therapeutic programs would be suspended due to being infected to SARS-CoV-2. We focused the existing data in this regard through searching on PubMed, Google Scholar, and Scopus and tried to summarize recommendations for treating this group of patients in COVID era to provide a practical guide for clinicians.

Recent Findings: The number of diagnosed skin cancers dropped significantly since the beginning of the pandemic, specially in the peaks of various variants of the SARS-CoV-2 infection. The new guidelines allowed even a 3-month delay in excision and recommended surgery for non-melanoma growing skin cancers.

Conclusion: Dermatologists should perform a careful, individualized risk-benefit assessment for their patients and consider some changes in routine protocols such as having a delayed diagnostic or therapeutic intervention.

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References

Conforti C, Giuffrida R, Di Meo N, Zalaudek I . Management of advanced melanoma in the COVID-19 era. Dermatol Ther. 2020; 33(4):e13444. PMC: 7235483. DOI: 10.1111/dth.13444. View

Ricci F, Fania L, Paradisi A, Di Lella G, Pallotta S, Sobrino L . Delayed melanoma diagnosis in the COVID-19 era: increased breslow thickness in primary melanomas seen after the COVID-19 lockdown. J Eur Acad Dermatol Venereol. 2020; 34(12):e778-e779. PMC: 7436601. DOI: 10.1111/jdv.16874. View

Andrew T, Alrawi M, Lovat P . Reduction in skin cancer diagnoses in the UK during the COVID-19 pandemic. Clin Exp Dermatol. 2020; 46(1):145-146. PMC: 7436874. DOI: 10.1111/ced.14411. View

Nahm S, Rembielak A, Peach H, Lorigan P . Consensus Guidelines for the Management of Melanoma during the COVID-19 Pandemic: Surgery, Systemic Anti-cancer Therapy, Radiotherapy and Follow-up. Clin Oncol (R Coll Radiol). 2020; 33(1):e54-e57. PMC: 7328577. DOI: 10.1016/j.clon.2020.06.017. View

Mohseni Afshar Z, Hosseinzadeh R, Barary M, Ebrahimpour S, Alijanpour A, Sayad B . Challenges posed by COVID-19 in cancer patients: A narrative review. Cancer Med. 2021; 11(4):1119-1135. PMC: 8855916. DOI: 10.1002/cam4.4519. View

Cocuz I, Cocuz M, Niculescu R, Sincu M, Tinca A, Sabau A . The Impact of and Adaptations Due to the COVID-19 Pandemic on the Histopathological Diagnosis of Skin Pathologies, Including Non-Melanocyte and Melanoma Skin Cancers-A Single-Center Study in Romania. Medicina (Kaunas). 2021; 57(6). PMC: 8226979. DOI: 10.3390/medicina57060533. View

Puig S, Berrocal A . Management of high-risk and advanced basal cell carcinoma. Clin Transl Oncol. 2015; 17(7):497-503. PMC: 4495248. DOI: 10.1007/s12094-014-1272-9. View

Silvestris N, Di Maio M, Russo A, Chiari R, De Giorgi U, Del Mastro L . COVID-19 infection in cancer patients: what has been the contribution of Associazione Italiana Oncologia Medica (AIOM) to oncological care since the beginning of the first pandemic wave?. ESMO Open. 2021; 6(2):100100. PMC: 7973080. DOI: 10.1016/j.esmoop.2021.100100. View

Schauer A, Kulakov E, Martyn-Simmons C, Bunker C, Edmonds E . Melanoma defies 'lockdown': ongoing detection during Covid-19 in central London. Clin Exp Dermatol. 2020; 45(7):900. PMC: 7300539. DOI: 10.1111/ced.14324. View

10.

Ferrara G, De Vincentiis L, Ambrosini-Spaltro A, Barbareschi M, Bertolini V, Contato E . Cancer Diagnostic Delay in Northern and Central Italy During the 2020 Lockdown Due to the Coronavirus Disease 2019 Pandemic. Am J Clin Pathol. 2020; 155(1):64-68. PMC: 7543252. DOI: 10.1093/ajcp/aqaa177. View

11.

Loh C, Chong Tam S, Oh C . Teledermatology in the COVID-19 pandemic: A systematic review. JAAD Int. 2021; 5:54-64. PMC: 8326016. DOI: 10.1016/j.jdin.2021.07.007. View

12.

Conforti C, Di Meo N, Giuffrida R, Zalaudek I . Management of patients with melanoma and non-melanoma skin cancers in the coronavirus disease 2019 era. Chin Med J (Engl). 2020; 133(17):2017-2019. PMC: 7478385. DOI: 10.1097/CM9.0000000000000930. View

13.

Lallas A, Kyrgidis A, Manoli S, Papageorgiou C, Lallas K, Sotiriou E . Delayed skin cancer diagnosis in 2020 because of the COVID-19-related restrictions: Data from an institutional registry. J Am Acad Dermatol. 2021; 85(3):721-723. PMC: 8156834. DOI: 10.1016/j.jaad.2021.05.021. View

14.

van Not O, van Breeschoten J, van den Eertwegh A, Hilarius D, de Meza M, Haanen J . The unfavorable effects of COVID-19 on Dutch advanced melanoma care. Int J Cancer. 2021; 150(5):816-824. PMC: 8652896. DOI: 10.1002/ijc.33833. View

15.

Degeling K, Baxter N, Emery J, Jenkins M, Franchini F, Gibbs P . An inverse stage-shift model to estimate the excess mortality and health economic impact of delayed access to cancer services due to the COVID-19 pandemic. Asia Pac J Clin Oncol. 2021; 17(4):359-367. PMC: 8014813. DOI: 10.1111/ajco.13505. View

16.

Conforti C, Paolini F, Venuti A, Dianzani C, Zalaudek I . The detection rate of human papillomavirus in well-differentiated squamous cell carcinoma and keratoacanthoma: is there new evidence for a viral pathogenesis of keratoacanthoma?. Br J Dermatol. 2019; 181(6):1309-1311. DOI: 10.1111/bjd.18212. View

17.

Asai Y, Nguyen P, Hanna T . Impact of the COVID-19 pandemic on skin cancer diagnosis: A population-based study. PLoS One. 2021; 16(3):e0248492. PMC: 8011724. DOI: 10.1371/journal.pone.0248492. View

18.

Tagliaferri L, Di Stefani A, Schinzari G, Fionda B, Rossi E, Del Regno L . Skin cancer triage and management during COVID-19 pandemic. J Eur Acad Dermatol Venereol. 2020; 34(6):1136-1139. PMC: 7267372. DOI: 10.1111/jdv.16529. View

19.

Pavia G, Gargiulo L, Valenti M, Facheris P, Nucca O, Narcisi A . Skin cancers: how to balance the risks and benefits of surgery during COVID-19 pandemic (a Northern Italy single-center experience). Int J Dermatol. 2020; 59(10):1287-1289. PMC: 7436394. DOI: 10.1111/ijd.15086. View

20.

Gomolin T, Cline A, Handler M . The danger of neglecting melanoma during the COVID-19 pandemic. J Dermatolog Treat. 2020; 31(5):444-445. DOI: 10.1080/09546634.2020.1762844. View