» Articles » PMID: 37405509

Reconstruction, Oversewing, or Taking the Anastomosis Down - Which Surgical Intervention is Most Potent in the Treatment of Anastomotic Leaks Following Colorectal Resections?

Overview
Specialty General Surgery
Date 2023 Jul 5
PMID 37405509
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose: Anastomotic leak (AL) following colorectal resections can be treated interventionally. However, most cases require surgical intervention. Thus, several surgical techniques are available, which intend to affect the further course positively. The aim of this retrospective analysis is to determine which surgical technique proves to have the biggest potential in reducing the morbidity and mortality as well as to minimize the need of re-interventions after AL.

Methods: All patients with a history of AL following colorectal resection between 2008 and 2020 were analyzed. Patient's outcomes following surgical treatment of AL, including morbidity and mortality, clinical and para-clinical (laboratory examinations, ultrasound, and CT-scan) detection of AL recurrence, re-intervention rate, and the length of hospital stay were documented and correlated with the surgical technique used (e.g. simply over-sewing the AL, over-sewing the AL with the construction of a protective ileostomy, resection and reconstruction of the anastomosis, peritoneal lavage and transanal drainage, or taking the anastomosis down and constructing an end stoma).

Results: A total of 2,724 colorectal resections were documented. Grade C AL occurred in 92 (4.4% AL occurrence-rate) and 31 (7.2% AL occurrence-rate) cases following colon and rectal resections, respectively. The anastomosis was not preservable in 52 and 17 cases following colon and rectal resections, respectively. Therefore, the anastomosis had been taken down and an end-stoma had been constructed. Over-sewing the AL with the construction of a protective ileostomy had the highest anastomosis preservation rate (14 of 18 cases) and lowest re-intervention rate (mean value of 1.5 re-interventions) following colon and rectal resections (7 of 9 cases; mean value, 1.5 re-interventions).

Conclusion: In cases where an AL is preservable, over-sewing the anastomosis and constructing a protective ileostomy has the greatest potential for positive short-term outcomes following colorectal resections.

Citing Articles

[Anastomotic leaks in colorectal surgery].

von Heesen M, Ghadimi M Chirurgie (Heidelb). 2024; 95(11):878-886.

PMID: 39387920 DOI: 10.1007/s00104-024-02180-0.

References
1.
Dulskas A, Kuliavas J, Sirvys A, Bausys A, Kryzauskas M, Bickaite K . Anastomotic Leak Impact on Long-Term Survival after Right Colectomy for Cancer: A Propensity-Score-Matched Analysis. J Clin Med. 2022; 11(15). PMC: 9369268. DOI: 10.3390/jcm11154375. View

2.
Kryzauskas M, Bausys A, Degutyte A, Abeciunas V, Poskus E, Bausys R . Risk factors for anastomotic leakage and its impact on long-term survival in left-sided colorectal cancer surgery. World J Surg Oncol. 2020; 18(1):205. PMC: 7427291. DOI: 10.1186/s12957-020-01968-8. View

3.
Gessler B, Eriksson O, Angenete E . Diagnosis, treatment, and consequences of anastomotic leakage in colorectal surgery. Int J Colorectal Dis. 2017; 32(4):549-556. PMC: 5355508. DOI: 10.1007/s00384-016-2744-x. View

4.
Buhr H, Klinger C, Lehmann K, Strahwald B, Rieger A . [German Society for General and Visceral Surgery (DGAV) risk calculator of interventions for colorectal cancer : Presentation of a surgical algorithm on patient participation and quality assurance]. Chirurg. 2019; 90(4):287-292. DOI: 10.1007/s00104-019-0936-y. View

5.
Alberts J, Parvaiz A, Moran B . Predicting risk and diminishing the consequences of anastomotic dehiscence following rectal resection. Colorectal Dis. 2003; 5(5):478-82. DOI: 10.1046/j.1463-1318.2003.00515.x. View