» Articles » PMID: 37370605

Design and Additive Manufacturing of Acetabular Implant with Continuously Graded Porosity

Overview
Date 2023 Jun 28
PMID 37370605
Authors
Affiliations
Soon will be listed here.
Abstract

Porous structured metallic implants are preferable as bone graft substitutes due to their faster tissue integration mediated by bone in-growth and vascularization. The porous scaffolds/implants should also mimic the graded structure of natural bone to ensure a match of mechanical properties. This article presents a method for designing a graded porous structured acetabular implant and identifies suitable parameters for manufacturing the model through additive manufacturing. The design method is based on slice-wise modification to ensure continuity of gradation. Modification of the slices was achieved through the binary image processing route. A geodesic dome-type design was adopted for developing the acetabular cup model from the graded porous structure. The model had a solid shell with the target porosity and pore size gradually changing from 65% and 950 µm, respectively, in the inner side to 75% and 650 µm, respectively, towards the periphery. The required dimensions of the unit structures and the combinations of pore structure and strut diameter necessary to obtain the target porosity and pore size were determined analytically. Suitable process parameters were identified to manufacture the model by Direct Metal Laser Sintering (DMLS) using Ti6Al4V powder after carrying out a detailed experimental study to minimize the variation of surface roughness and warping over different build angles of the strut structures. Dual-contour scanning was implemented to simplify the scan strategy. The minimum diameter of struts that could be manufactured using the selected scanning strategy and scanning parameters was found to be 375 µm. Finally, the model was built and from the micro-CT data, the porosities and pore sizes were found to be closely conforming to the designed values. The stiffness of the structures, as found from compression testing, was also found to match with that of human trabecular bone well. Further, the structure exhibited compliant bending-dominated behaviour under compressive loading.

Citing Articles

Titanium Alloy Implants with Lattice Structures for Mandibular Reconstruction.

Hijazi K, Dixon S, Armstrong J, Rizkalla A Materials (Basel). 2024; 17(1).

PMID: 38203994 PMC: 10779528. DOI: 10.3390/ma17010140.


Evaluation of Gelatin/Hyaluronic Acid-Generated Bridging in a 3D-Printed Titanium Cage for Bone Regeneration.

Park S, Farwa U, Hossain M, Im S, Lee B J Funct Biomater. 2023; 14(12).

PMID: 38132816 PMC: 10743693. DOI: 10.3390/jfb14120562.


Resorbable GBR Scaffolds in Oral and Maxillofacial Tissue Engineering: Design, Fabrication, and Applications.

Alavi S, Gholami M, Ebrahimi Shahmabadi H, Reher P J Clin Med. 2023; 12(22).

PMID: 38002577 PMC: 10672220. DOI: 10.3390/jcm12226962.


Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches.

Choi J, Lee E, Jang W, Kwon S J Funct Biomater. 2023; 14(10).

PMID: 37888162 PMC: 10607080. DOI: 10.3390/jfb14100497.


The Porosity Design and Deformation Behavior Analysis of Additively Manufactured Bone Scaffolds through Finite Element Modelling and Mechanical Property Investigations.

Rasheed S, Lughmani W, Khan M, Brabazon D, Obeidi M, Ahad I J Funct Biomater. 2023; 14(10).

PMID: 37888161 PMC: 10607099. DOI: 10.3390/jfb14100496.


References
1.
Liu R, Su Y, Yang W, Wu K, Du R, Zhong Y . A Novel Design Method of Gradient Porous Structure for Stabilized and Lightweight Mandibular Prosthesis. Bioengineering (Basel). 2022; 9(9). PMC: 9495853. DOI: 10.3390/bioengineering9090424. View

2.
Yan C, Hao L, Hussein A, Young P . Ti-6Al-4V triply periodic minimal surface structures for bone implants fabricated via selective laser melting. J Mech Behav Biomed Mater. 2015; 51:61-73. DOI: 10.1016/j.jmbbm.2015.06.024. View

3.
Karageorgiou V, Kaplan D . Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials. 2005; 26(27):5474-91. DOI: 10.1016/j.biomaterials.2005.02.002. View

4.
Taniguchi N, Fujibayashi S, Takemoto M, Sasaki K, Otsuki B, Nakamura T . Effect of pore size on bone ingrowth into porous titanium implants fabricated by additive manufacturing: An in vivo experiment. Mater Sci Eng C Mater Biol Appl. 2015; 59:690-701. DOI: 10.1016/j.msec.2015.10.069. View

5.
Li J, Li S, van Blitterswijk C, de Groot K . A novel porous Ti6Al4V: characterization and cell attachment. J Biomed Mater Res A. 2005; 73(2):223-33. DOI: 10.1002/jbm.a.30278. View