Three-dimensional Strategies in the Quantitative Resolution of Kinetic UV Absorbance Measurements for Monitoring the Oxidation of Quercetin by Oxidant Agents and Analyzing Dietary Supplement Product

Overview

Journal J Food Drug Anal

Specialties Nutritional Sciences
Pharmacology
Toxicology

Date 2023 Jun 19

PMID 37335156

Authors

Erdal Dinc

Asiye Ucer

Nazangul Unal

Affiliations

Soon will be listed here.

Abstract

Three-dimensional strategies involving the application of parallel factor analysis (PARAFAC) to the kinetic UV absorbance measurements were elaborated to monitor the oxidation of quercetin with oxidant agents (KCrO and KIO) and to quantify analyte in a dietary supplement product. Loadings (spectral, kinetic and concentration profiles) were obtained by the PARAFAC deconvolution. Spectral identification, kinetics and quantification of the relevant analyte in the presence of interferent(s) were performed. The elaborated chemometric strategies were carefully validated to demonstrate the capability of the method. Assay results of the PARAFAC strategies were statistically compared to that of the newly developed UPLC method.

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