Genome and Atrial Fibrillation

Overview

Journal J Arrhythm

Publisher Wiley

Date 2023 Jun 16

PMID 37324776

Authors

Yukiko Nakano

Affiliations

Soon will be listed here.

Abstract

Atrial fibrillation (AF), the most common type of arrhythmia, can cause several adverse effects, such as stroke, heart failure, and cognitive dysfunction, also in addition to reducing quality of life and increasing mortality. Evidence suggests that AF is caused by a combination of genetic and clinical predispositions. In line with this, genetic studies on AF have progressed significantly through linkage studies, genome-wide association studies, use of polygenic risk scores, and studies on rare coding variations, gradually elucidating the relationship between genes and the pathogenesis and prognosis of AF. This article will review current trends in genetic analysis concerning AF.

Citing Articles

DNA Methylation and Telomeres-Their Impact on the Occurrence of Atrial Fibrillation during Cardiac Aging.

Grzeczka A, Graczyk S, Kordowitzki P Int J Mol Sci. 2023; 24(21).

PMID: 37958686 PMC: 10650750. DOI: 10.3390/ijms242115699.

Genome and atrial fibrillation.

Nakano Y J Arrhythm. 2023; 39(3):303-309.

PMID: 37324776 PMC: 10264727. DOI: 10.1002/joa3.12847.

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