The Effect of Liquid Silicone on the Rabbit Retina. Histologic and Ultrastructural Study

Overview

Journal Arch Ophthalmol

Publisher American Medical Association

Specialty Ophthalmology

Date 1986 Jul 1

PMID 3729775

Citations 23

Authors

M Gonvers

J P Hornung

C De Courten

Affiliations

Soon will be listed here.

Abstract

Silicone oil was injected into 23 rabbit eyes, which had undergone vitrectomy and which were then examined in the electron microscope six weeks later. Retinal lesions were observed in the outer plexiform layer. They consisted mainly of a subtotal disappearance of the processes of horizontal and bipolar cells and of the synaptic terminals of the photoreceptors. The lesions were seen only in areas of the retina that had been in permanent contact with the oil bubble. They did not depend on the purity of the silicone oil injected.

Citing Articles

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Microstructural and hemodynamic changes in the fundus after pars plana vitrectomy for different vitreoretinal diseases.

Li D, Chen H, Huang S, Jia B, Lu L, Fu J Graefes Arch Clin Exp Ophthalmol. 2023; 262(7):1977-1992.

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Clinical Outcome of Cystoid Macular Edema in Silicone Oil-Filled Eyes.

Shaheen A, Lai J, Magraner M, Ashkenazy N, Flynn Jr H, Sridhar J J Vitreoretin Dis. 2023; 7(6):477-482.

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Early vascular changes after silicone oil removal using optical coherence tomography angiography.

Hou Y, Liu L, Wang G, Xie J, Wang Y BMC Ophthalmol. 2023; 23(1):128.

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Unexplained visual loss after primary pars-plana-vitrectomy with silicone oil tamponade in fovea-sparing retinal detachment.

Barth T, Helbig H, Maerker D, Gamulescu M, Radeck V BMC Ophthalmol. 2023; 23(1):75.

PMID: 36829157 PMC: 9951486. DOI: 10.1186/s12886-023-02823-6.