Sex, Aging, Immunity and Adrenal Cancer

Overview

Journal Nat Aging

Specialty Geriatrics

Date 2023 Jun 8

PMID 37291221

Authors

Ashley Townsel

Curtis J Henry

Affiliations

Soon will be listed here.

References

Austad S . Why women live longer than men: sex differences in longevity. Gend Med. 2006; 3(2):79-92. DOI: 10.1016/s1550-8579(06)80198-1. View

Warde K, Smith L, Liu L, Stubben C, Lohman B, Willett P . Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner. Nat Aging. 2023; 3(7):846-865. PMC: 11534150. DOI: 10.1038/s43587-023-00420-2. View

Campisi J, dAdda di Fagagna F . Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol. 2007; 8(9):729-40. DOI: 10.1038/nrm2233. View

Faget D, Ren Q, Stewart S . Unmasking senescence: context-dependent effects of SASP in cancer. Nat Rev Cancer. 2019; 19(8):439-453. DOI: 10.1038/s41568-019-0156-2. View

Childs B, Durik M, Baker D, van Deursen J . Cellular senescence in aging and age-related disease: from mechanisms to therapy. Nat Med. 2015; 21(12):1424-35. PMC: 4748967. DOI: 10.1038/nm.4000. View

Berthon A, Sahut-Barnola I, Lambert-Langlais S, De Joussineau C, Damon-Soubeyrand C, Louiset E . Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development. Hum Mol Genet. 2010; 19(8):1561-76. DOI: 10.1093/hmg/ddq029. View

Heaton J, Wood M, Kim A, Lima L, Barlaskar F, Almeida M . Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin. Am J Pathol. 2012; 181(3):1017-33. PMC: 3432433. DOI: 10.1016/j.ajpath.2012.05.026. View

Stanworth R, Jones T . Testosterone for the aging male; current evidence and recommended practice. Clin Interv Aging. 2008; 3(1):25-44. PMC: 2544367. DOI: 10.2147/cia.s190. View

Altieri P, Barisione C, Lazzarini E, Garuti A, Bezante G, Canepa M . Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes. J Am Heart Assoc. 2016; 5(1). PMC: 4859360. DOI: 10.1161/JAHA.115.002383. View

10.

OConnor K, Ferrell R, Brindle E, Trumble B, Shofer J, Holman D . Progesterone and ovulation across stages of the transition to menopause. Menopause. 2009; 16(6):1178-87. PMC: 2783957. DOI: 10.1097/gme.0b013e3181aa192d. View

11.

Sasaki Y, Ikeda Y, Uchikado Y, Akasaki Y, Sadoshima J, Ohishi M . Estrogen Plays a Crucial Role in Rab9-Dependent Mitochondrial Autophagy, Delaying Arterial Senescence. J Am Heart Assoc. 2021; 10(7):e019310. PMC: 8174372. DOI: 10.1161/JAHA.120.019310. View

12.

Atif F, Yousuf S, Espinosa-Garcia C, Sergeeva E, Stein D . Progesterone Treatment Attenuates Glycolytic Metabolism and Induces Senescence in Glioblastoma. Sci Rep. 2019; 9(1):988. PMC: 6353890. DOI: 10.1038/s41598-018-37399-5. View

13.

Nagy L, Szanto A, Szatmari I, Szeles L . Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response. Physiol Rev. 2012; 92(2):739-89. DOI: 10.1152/physrev.00004.2011. View

14.

Hamilton J, Henry C . Aging and immunotherapies: New horizons for the golden ages. Aging Cancer. 2022; 1(1-4):30-44. PMC: 9307207. DOI: 10.1002/aac2.12014. View