Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2023 May 27

PMID 37243132

Authors

Ivana Papezikova

Veronika Piackova

Iva Dykova

Ali Asghar Baloch

Hana Kocour Kroupova

Eliska Zuskova

Lubomir Pojezdal

Hana Minarova

Eva Syrova

Hana Bandouchova

Pavel Hyrsl

Katerina Matejickova

Jiri Pikula

Miroslava Palikova

Affiliations

Soon will be listed here.

Abstract

In the present study, we describe a natural outbreak of carp edema virus disease (CEVD) in koi carp, concentrating on clinical manifestation, gross and microscopic pathology, immunological parameters, viral diagnostics, and phylogenetic analysis. Examination of white blood cell parameters showed increased monocyte and decreased lymphocyte counts in CEV-affected fish compared to healthy control fish. Regarding immune system functioning, the present work shows, for the first time, enhanced phagocytic activity in CEV-affected fish. Respiratory burst of phagocytes was strongly increased in diseased fish, the increase being attributed to an increased phagocyte count rather than enhancement of their metabolic activity. The present work also newly shows histopathological changes in the pancreatic tissue of diseased koi.

Citing Articles

Carp edema virus surveillance in the koi trade: early detection through shipping environment sampling and longitudinal monitoring of CEV outbreaks in a wholesaler facility.

Montacq L, Baud M, Giummarra H, Flores D, Pallandre L, Caubet C Vet Res. 2025; 56(1):48.

PMID: 40038754 PMC: 11881292. DOI: 10.1186/s13567-025-01476-1.

Case report: Carp edema virus infection in overwintering fish.

Palikova M, Balazova A, Pojezdal L, Papezikova I, Mikulikova I, Toulova I Front Vet Sci. 2025; 12:1532861.

PMID: 40027355 PMC: 11868120. DOI: 10.3389/fvets.2025.1532861.

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