Crotonylation of PRKACA Enhances PKA Activity and Promotes Colorectal Cancer Development Via the PKA-FAK-AKT Pathway
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Citing Articles
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References
1.
Zhao J, Guan J
. Signal transduction by focal adhesion kinase in cancer. Cancer Metastasis Rev. 2009; 28(1-2):35-49.
DOI: 10.1007/s10555-008-9165-4.
View
2.
Miller K, Nogueira L, Mariotto A, Rowland J, Yabroff K, Alfano C
. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019; 69(5):363-385.
DOI: 10.3322/caac.21565.
View
3.
Bossis I, Stratakis C
. Minireview: PRKAR1A: normal and abnormal functions. Endocrinology. 2004; 145(12):5452-8.
DOI: 10.1210/en.2004-0900.
View
4.
Kim C, Xuong N, Taylor S
. Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science. 2005; 307(5710):690-6.
DOI: 10.1126/science.1104607.
View
5.
Xu W, Wan J, Zhan J, Li X, He H, Shi Z
. Global profiling of crotonylation on non-histone proteins. Cell Res. 2017; 27(7):946-949.
PMC: 5518986.
DOI: 10.1038/cr.2017.60.
View