Effect of Single-port Video-assisted Thoracoscopy on Surgical Site Wound Infection and Healing in Patients with Lung Cancer: A Meta-analysis

Overview

Journal Int Wound J

Specialties Emergency Medicine
Orthopedics

Date 2023 May 16

PMID 37193587

Authors

Wenqi Wu

Yan Zhao

Zhe Zhang

Jingyuan Jiang

Chong Feng

Dongliang Qin

Chen Zhang

Zhenan Xu

Lening Zhang

Fengwu Lin

Affiliations

Soon will be listed here.

Abstract

We performed a meta-analysis to comprehensively assess the effect of single-port video-assisted thoracoscopy on surgical site wound infection and healing in patients with lung cancer. A computerised search for studies on single-port video-assisted thoracoscopy treatment of lung cancer was conducted from the time of database creation through February 2023 using the PubMed, EMBASE, the Cochrane Library, China National Knowledge Infrastructure, and Wanfang databases. Two investigators independently screened the literature, extracted information, and evaluated the quality of studies according to inclusion and exclusion criteria. Either a fixed or random-effects model was used in calculating the relative risk (RR) with 95% confidence intervals (CIs). Meta-analysis was performed using RevMan 5.4 software. The results showed that, compared with multi-port video-assisted thoracoscopy, single-port video-assisted thoracoscopy significantly reduced surgical site wound infection (RR: 0.38, 95% CI: 0.19-0.77, P = .007) and significantly promoted wound healing (RR: 0.37, 95% CI: 0.22-0.64, P < .001). Compared with multi-port video-assisted thoracoscopy, single-port video-assisted thoracoscopy significantly reduced surgical site wound infections and also promoted wound healing. However, because of large variations in study sample sizes, some of the literature reported methods of inferior quality. Additional high-quality studies containing large sample sizes are needed to further validate these results.

Citing Articles

RETRACTION: Effect of Single-Port Video-Assisted Thoracoscopy on Surgical Site Wound Infection and Healing in Patients With Lung Cancer: A Meta-Analysis.

Int Wound J. 2025; 22(3):e70300.

PMID: 40049700 PMC: 11884898. DOI: 10.1111/iwj.70300.

Evolution of uniportal video-assisted thoracoscopic surgery: optimization and advancements.

Laven I, Verkoulen K, Franssen A, Hulsewe K, Vissers Y, Stupnik T J Thorac Dis. 2024; 16(8):4839-4843.

PMID: 39268107 PMC: 11388257. DOI: 10.21037/jtd-24-647.

Effect of single-port video-assisted thoracoscopy on surgical site wound infection and healing in patients with lung cancer: A meta-analysis.

Wu W, Zhao Y, Zhang Z, Jiang J, Feng C, Qin D Int Wound J. 2023; 20(9):3483-3490.

PMID: 37193587 PMC: 10588324. DOI: 10.1111/iwj.14220.

References

Takeuchi M, Obara H, Kawakubo H, Shinoda M, Okabayashi K, Mayanagi S . Comparison of olanexidine versus povidone-iodine for preventing surgical site infection in gastrointestinal surgery: study protocol for a multicentre, single-blind, randomised controlled clinical trial. BMJ Open. 2019; 9(5):e028269. PMC: 6549615. DOI: 10.1136/bmjopen-2018-028269. View

Zhao R, Shi Z, Cheng S . Uniport video assisted thoracoscopic surgery (U-VATS) exhibits increased feasibility, non-inferior tolerance, and equal efficiency compared with multiport VATS and open thoracotomy in the elderly non-small cell lung cancer patients at early stage. Medicine (Baltimore). 2019; 98(28):e16137. PMC: 6641850. DOI: 10.1097/MD.0000000000016137. View

Jutley R, Khalil M, Rocco G . Uniportal vs standard three-port VATS technique for spontaneous pneumothorax: comparison of post-operative pain and residual paraesthesia. Eur J Cardiothorac Surg. 2005; 28(1):43-6. DOI: 10.1016/j.ejcts.2005.02.039. View

Sung H, Ferlay J, Siegel R, Laversanne M, Soerjomataram I, Jemal A . Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021; 71(3):209-249. DOI: 10.3322/caac.21660. View

Dai F, Meng S, Mei L, Guan C, Ma Z . Single-port video-assisted thoracic surgery in the treatment of non-small cell lung cancer: a propensity-matched comparative analysis. J Thorac Dis. 2016; 8(10):2872-2878. PMC: 5107542. DOI: 10.21037/jtd.2016.10.27. View

Bade B, Dela Cruz C . Lung Cancer 2020: Epidemiology, Etiology, and Prevention. Clin Chest Med. 2020; 41(1):1-24. DOI: 10.1016/j.ccm.2019.10.001. View

Huang L, Kehlet H, Petersen R . Effect of posture on pulmonary function and oxygenation after fast-tracking video-assisted thoracoscopic surgery (VATS) lobectomy: a prospective pilot study. Perioper Med (Lond). 2021; 10(1):26. PMC: 8411530. DOI: 10.1186/s13741-021-00199-z. View

Liu H, Chiang X, Hung M, Wang M, Lin M, Cheng Y . Nonintubated uniportal thoracoscopic segmentectomy for lung cancer. J Formos Med Assoc. 2020; 119(9):1396-1404. DOI: 10.1016/j.jfma.2020.03.021. View

Gonzalez-Rivas D, de la Torre M, Fernandez R, Mosquera V . Single-port video-assisted thoracoscopic left upper lobectomy. Interact Cardiovasc Thorac Surg. 2011; 13(5):539-41. DOI: 10.1510/icvts.2011.274746. View

10.

Li T, Xia L, Wang J, Xu S, Sun X, Xu M . Uniportal versus three-port video-assisted thoracoscopic surgery for non-small cell lung cancer: A retrospective study. Thorac Cancer. 2021; 12(8):1147-1153. PMC: 8046032. DOI: 10.1111/1759-7714.13882. View

11.

Yang J, Zhu J, Zhang Y, Chen Y, Ding L, Kensler T . Lung Cancer in a Rural Area of China: Rapid Rise in Incidence and Poor Improvement in Survival. Asian Pac J Cancer Prev. 2015; 16(16):7295-302. DOI: 10.7314/apjcp.2015.16.16.7295. View

12.

Han D, Cao Y, Wu H, Wang H, Jiang L, Zhao D . Uniportal video-assisted thoracic surgery for the treatment of lung cancer: a consensus report from Chinese Society for Thoracic and Cardiovascular Surgery (CSTCVS) and Chinese Association of Thoracic Surgeons (CATS). Transl Lung Cancer Res. 2020; 9(4):971-987. PMC: 7481589. DOI: 10.21037/tlcr-20-576. View

13.

Bourdages-Pageau E, Vieira A, Lacasse Y, Figueroa P . Outcomes of Uniportal vs Multiportal Video-Assisted Thoracoscopic Lobectomy. Semin Thorac Cardiovasc Surg. 2019; 32(1):145-151. DOI: 10.1053/j.semtcvs.2019.05.021. View

14.

Ettinger D, Aisner D, Wood D, Akerley W, Bauman J, Chang J . NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 5.2018. J Natl Compr Canc Netw. 2018; 16(7):807-821. DOI: 10.6004/jnccn.2018.0062. View

15.

Nwogu C, DCunha J, Pang H, Gu L, Wang X, Richards W . VATS lobectomy has better perioperative outcomes than open lobectomy: CALGB 31001, an ancillary analysis of CALGB 140202 (Alliance). Ann Thorac Surg. 2014; 99(2):399-405. PMC: 5616174. DOI: 10.1016/j.athoracsur.2014.09.018. View

16.

Wu W, Zhao Y, Zhang Z, Jiang J, Feng C, Qin D . Effect of single-port video-assisted thoracoscopy on surgical site wound infection and healing in patients with lung cancer: A meta-analysis. Int Wound J. 2023; 20(9):3483-3490. PMC: 10588324. DOI: 10.1111/iwj.14220. View

17.

Li J, Qiu B, Scarci M, Rocco G, Gao S . Uniportal video-assisted thoracic surgery could reduce postoperative thorax drainage for lung cancer patients. Thorac Cancer. 2019; 10(6):1334-1339. PMC: 6558522. DOI: 10.1111/1759-7714.13040. View

18.

Hirai K, Usuda J . Uniportal video-assisted thoracic surgery reduced the occurrence of post-thoracotomy pain syndrome after lobectomy for lung cancer. J Thorac Dis. 2019; 11(9):3896-3902. PMC: 6790455. DOI: 10.21037/jtd.2019.09.07. View

19.

Yu J, Soulos P, Cramer L, Decker R, Kim A, Gross C . Comparative effectiveness of surgery and radiosurgery for stage I non-small cell lung cancer. Cancer. 2015; 121(14):2341-9. PMC: 4490059. DOI: 10.1002/cncr.29359. View