Case Report: Transient Symptoms of Autism Spectrum Disorder in a 2-year-old Boy

Overview

Journal Clin Case Rep

Date 2023 May 14

PMID 37180323

Authors

Devon N Gangi

Ramkumar Aishworiya

Monique Moore Hill

Dan Thu Nguyen

Rachel Ni

Chandni Parikh

Erika Solis

Sally Ozonoff

Affiliations

Soon will be listed here.

Abstract

Though early ASD diagnosis is highly stable, this case report describes a rare situation in which symptoms resolved without intervention over a 4 month period. We do not recommend delaying diagnosis in symptomatic children who meet criteria but when major behavioral changes are reported after diagnosis, reevaluation may be beneficial.

Citing Articles

Toddler Screen Time: Longitudinal Associations with Autism and ADHD Symptoms and Developmental Outcomes.

Hill M, Gangi D, Miller M Child Psychiatry Hum Dev. 2024; .

PMID: 39609334 DOI: 10.1007/s10578-024-01785-0.

Case report: Transient symptoms of autism spectrum disorder in a 2-year-old boy.

Gangi D, Aishworiya R, Hill M, Nguyen D, Ni R, Parikh C Clin Case Rep. 2023; 11(5):e07345.

PMID: 37180323 PMC: 10172454. DOI: 10.1002/ccr3.7345.

References

Kushima M, Kojima R, Shinohara R, Horiuchi S, Otawa S, Ooka T . Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age: The Japan Environment and Children's Study. JAMA Pediatr. 2022; 176(4):384-391. PMC: 8804971. DOI: 10.1001/jamapediatrics.2021.5778. View

Wagner L, Corona L, Weitlauf A, Marsh K, Berman A, Broderick N . Use of the TELE-ASD-PEDS for Autism Evaluations in Response to COVID-19: Preliminary Outcomes and Clinician Acceptability. J Autism Dev Disord. 2020; 51(9):3063-3072. PMC: 7596626. DOI: 10.1007/s10803-020-04767-y. View

McArthur B, Volkova V, Tomopoulos S, Madigan S . Global Prevalence of Meeting Screen Time Guidelines Among Children 5 Years and Younger: A Systematic Review and Meta-analysis. JAMA Pediatr. 2022; 176(4):373-383. PMC: 8845032. DOI: 10.1001/jamapediatrics.2021.6386. View

Coughlan B, van IJzendoorn M, Woolgar M, Weisblatt E, Duschinsky R . Differentiating "Attachment Difficulties" From Autism Spectrum Disorders and Attention Deficit Hyperactivity Disorder: Qualitative Interviews With Experienced Health Care Professionals. Front Psychol. 2022; 12:780128. PMC: 8860234. DOI: 10.3389/fpsyg.2021.780128. View

Barnevik Olsson M, Westerlund J, Lundstrom S, Giacobini M, Fernell E, Gillberg C . "Recovery" from the diagnosis of autism - and then?. Neuropsychiatr Dis Treat. 2015; 11:999-1005. PMC: 4397923. DOI: 10.2147/NDT.S78707. View

Shuffrey L, Firestein M, Kyle M, Fields A, Alcantara C, Amso D . Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection. JAMA Pediatr. 2022; 176(6):e215563. PMC: 8728661. DOI: 10.1001/jamapediatrics.2021.5563. View

Ozonoff S, Young G, Landa R, Brian J, Bryson S, Charman T . Diagnostic stability in young children at risk for autism spectrum disorder: a baby siblings research consortium study. J Child Psychol Psychiatry. 2015; 56(9):988-98. PMC: 4532646. DOI: 10.1111/jcpp.12421. View

Trott M, Driscoll R, Irlado E, Pardhan S . Changes and correlates of screen time in adults and children during the COVID-19 pandemic: A systematic review and meta-analysis. EClinicalMedicine. 2022; 48:101452. PMC: 9122783. DOI: 10.1016/j.eclinm.2022.101452. View

Gangi D, Aishworiya R, Hill M, Nguyen D, Ni R, Parikh C . Case report: Transient symptoms of autism spectrum disorder in a 2-year-old boy. Clin Case Rep. 2023; 11(5):e07345. PMC: 10172454. DOI: 10.1002/ccr3.7345. View

10.

Pierce K, Gazestani V, Bacon E, Barnes C, Cha D, Nalabolu S . Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months. JAMA Pediatr. 2019; 173(6):578-587. PMC: 6547081. DOI: 10.1001/jamapediatrics.2019.0624. View

11.

Shulman L, DAgostino E, Lee S, Valicenti-McDermott M, Seijo R, Tulloch E . When an Early Diagnosis of Autism Spectrum Disorder Resolves, What Remains?. J Child Neurol. 2019; 34(7):382-386. DOI: 10.1177/0883073819834428. View

12.

Kelley E, Paul J, Fein D, Naigles L . Residual language deficits in optimal outcome children with a history of autism. J Autism Dev Disord. 2006; 36(6):807-28. DOI: 10.1007/s10803-006-0111-4. View

13.

Pouretemad H, Sadeghi S, Badv R, Brand S . Differentiating Post-Digital Nannying Autism Syndrome from Autism Spectrum Disorders in Young Children: A Comparative Cross-Sectional Study. J Clin Med. 2022; 11(22). PMC: 9693544. DOI: 10.3390/jcm11226786. View

14.

Jones E, Gliga T, Bedford R, Charman T, Johnson M . Developmental pathways to autism: a review of prospective studies of infants at risk. Neurosci Biobehav Rev. 2013; 39:1-33. PMC: 3969297. DOI: 10.1016/j.neubiorev.2013.12.001. View

15.

Rutter M, Beckett C, Bredenkamp D, Castle J, Groothues C, Kreppner J . Quasi-autistic patterns following severe early global privation. English and Romanian Adoptees (ERA) Study Team. J Child Psychol Psychiatry. 1999; 40(4):537-49. View

16.

Zwaigenbaum L, Bauman M, Choueiri R, Kasari C, Carter A, Granpeesheh D . Early Intervention for Children With Autism Spectrum Disorder Under 3 Years of Age: Recommendations for Practice and Research. Pediatrics. 2015; 136 Suppl 1:S60-81. PMC: 9923898. DOI: 10.1542/peds.2014-3667E. View

17.

Figueiredo C, Fontes-Dantas F, Da Poian A, Clarke J . SARS-CoV-2-associated cytokine storm during pregnancy as a possible risk factor for neuropsychiatric disorder development in post-pandemic infants. Neuropharmacology. 2021; 201:108841. PMC: 8519783. DOI: 10.1016/j.neuropharm.2021.108841. View

18.

Wetherby A, Brosnan-Maddox S, Peace V, Newton L . Validation of the Infant-Toddler Checklist as a broadband screener for autism spectrum disorders from 9 to 24 months of age. Autism. 2008; 12(5):487-511. PMC: 2663025. DOI: 10.1177/1362361308094501. View

19.

Mulkey S, Williams M, Jadeed N, Zhang A, Israel S, DeBiasi R . Neurodevelopment in infants with antenatal or early neonatal exposure to SARS-CoV-2. Early Hum Dev. 2022; 175:105694. DOI: 10.1016/j.earlhumdev.2022.105694. View

20.

Wieckowski A, Williams L, Rando J, Lyall K, Robins D . Sensitivity and Specificity of the Modified Checklist for Autism in Toddlers (Original and Revised): A Systematic Review and Meta-analysis. JAMA Pediatr. 2023; 177(4):373-383. PMC: 9941975. DOI: 10.1001/jamapediatrics.2022.5975. View