Taste Vs. Pain: A Sensory Feast in Bacterial Meningitis
Overview
Overview
Journal
Cell Host Microbe
Publisher
Cell Press
Specialties
Infectious Diseases
Microbiology
Microbiology
Date
2023 May 11
PMID
37167946
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
During meningitis, sensory neurons detect bacterial toxins and metabolites. Early activation of pain receptors suppresses host defense in the meninges while, later, taste receptors amplify inflammation in the spinal cord. Is a neuroimmune axis a clue to new treatments?
Citing Articles
Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS.
Wyart C, Carbo-Tano M, Cantaut-Belarif Y, Orts-DelImmagine A, Bohm U Nat Rev Neurosci. 2023; 24(9):540-556.
PMID: 37558908 DOI: 10.1038/s41583-023-00723-8.