4D-Flow Cardiovascular Magnetic Resonance Sequence for Aortic Assessment: Multi-Vendor and Multi-Magnetic Field Reproducibility in Healthy Volunteers

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Apr 28

PMID 37109295

Authors

Bruna Punzo

Brigida Ranieri

Liberatore Tramontano

Ornella Affinito

Monica Franzese

Eduardo Bossone

Luca Saba

Carlo Cavaliere

Filippo Cademartiri

Affiliations

Soon will be listed here.

Abstract

Objectives: Four-dimensional (4D) flow cardiac magnetic resonance (CMR) represents an emerging technique for non-invasive evaluation of the aortic flow. The aim of this study was to investigate a 4D-flow CMR sequence for the assessment of thoracic aorta comparing different vendors and different magnetic fields of MR scanner in fifteen healthy volunteers.

Methods: CMR was performed on three different MRI scanners: one at 1.5 T and two at 3 T. Flow parameters and planar wall shear stress (WSS) were extracted from six transversal planes along the full thoracic aorta by three operators. Inter-vendor comparability as well as scan-rescan, intra- and interobserver reproducibility were examined.

Results: A high heterogeneity was found in the comparisons for each operator and for each scanner in the six transversal planes analysis (Friedman rank-sum test; -value ≤ 0.05). Among all, the most reproducible measures were extracted for the sinotubular junction plane and for the flow parameters.

Conclusions: Our results suggest that standardized procedures have to be defined to make more comparable and reproducible 4D-flow parameters and mainly, clinical impactfulness. Further studies on sequences development are needed to validate 4D-flow MRI assessment across vendors and magnetic fields also compared to a missing gold standard.

Citing Articles

Inter-site comparability of 4D flow cardiovascular magnetic resonance measurements in healthy traveling volunteers-a multi-site and multi-magnetic field strength study.

Muller M, Daud E, Langer G, Groschel J, Viezzer D, Hadler T Front Cardiovasc Med. 2024; 11:1456814.

PMID: 39582524 PMC: 11582008. DOI: 10.3389/fcvm.2024.1456814.

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