Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma

Overview

Journal Cancer Res

Specialty Oncology

Date 2023 Apr 14

PMID 37057874

Authors

Gia-Buu Tran

Jane Ding

Bingwei Ye

Mengling Liu

Yajie Yu

Yunhong Zha

Zheng Dong

Kebin Liu

Sunil Sudarshan

Han-Fei Ding

Affiliations

Soon will be listed here.

Abstract

Significance: Caffeine treatment and FOXM1 inhibition can both enhance the antitumor effect of statins by blocking the molecular and metabolic processes that confer statin resistance, indicating potential combination therapeutic strategies for neuroblastoma. See related commentary by Stouth et al., p. 2091.

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