» Articles » PMID: 37032416

Nutritional Quality and Biological Application of Mushroom Protein As a Novel Protein Alternative

Overview
Journal Curr Nutr Rep
Date 2023 Apr 9
PMID 37032416
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose Of Review: Global concerns about population growth, economic, and nutritional transitions and health have led to the search for a low-cost protein alternative to animal origins. This review provides an overview of the viability of exploring mushroom protein as a future protein alternative considering the nutritional value, quality, digestibility, and biological benefits.

Recent Findings: Plant proteins are commonly used as alternatives to animal proteins, but the majority of them are low in quality due to a lack of one or more essential amino acids. Edible mushroom proteins usually have a complete essential amino acid profile, meet dietary requirements, and provide economic advantages over animal and plant sources. Mushroom proteins may provide health advantages by eliciting antioxidant, antitumor, angiotensin-converting enzyme (ACE), inhibitory and antimicrobial properties over animal proteins. Protein concentrates, hydrolysates, and peptides from mushrooms are being used to improve human health. Also, edible mushrooms can be used to fortify traditional food to increase protein value and functional qualities. These characteristics highlight mushroom proteins as inexpensive, high-quality proteins that can be used as a meat alternative, as pharmaceuticals, and as treatments to alleviate malnutrition. Edible mushroom proteins are high in quality, low in cost, widely available, and meet environmental and social requirements, making them suitable as sustainable alternative proteins.

Citing Articles

Mushrooms as Nutritional Powerhouses: A Review of Their Bioactive Compounds, Health Benefits, and Value-Added Products.

Singh A, Saini R, Kumar A, Chawla P, Kaushik R Foods. 2025; 14(5).

PMID: 40077445 PMC: 11899115. DOI: 10.3390/foods14050741.


The Influence of the Divergent Substrate on Physicochemical Properties and Metabolite Profiling of Cultivation.

Mediatrice H, Aimable N, Claude I, Fallah N, Abdelkader M, Biregeya J J Fungi (Basel). 2025; 11(2).

PMID: 39997426 PMC: 11856532. DOI: 10.3390/jof11020132.


Wet pulverization combined with temperature cycling strategy for extraction of protein with attenuating hepatic steatosis on obese mice.

Liu P, Gao C, Li W, Chen W, Zhang Z, Wu D Food Chem X. 2025; 25:102170.

PMID: 39897974 PMC: 11782863. DOI: 10.1016/j.fochx.2025.102170.


Exploring Sustainable Future Protein Sources.

Oh Y, Kim H Food Sci Anim Resour. 2025; 45(1):81-108.

PMID: 39840240 PMC: 11743843. DOI: 10.5851/kosfa.2024.e111.


Against Colitis-Associated Cancer Through the Suppression of the PI3K/AKT/COX-2 Pathway and Inhibition of PGE2 Production in Mice.

Chen J, Liu S, Zhang X, Dai X, Li Y, Han Y Nutrients. 2024; 16(23).

PMID: 39683442 PMC: 11643906. DOI: 10.3390/nu16234048.


References
1.
Sangtitanu T, Sangtanoo P, Srimongkol P, Saisavoey T, Reamtong O, Karnchanatat A . Peptides obtained from edible mushrooms: Hericium erinaceus offers the ability to scavenge free radicals and induce apoptosis in lung cancer cells in humans. Food Funct. 2020; 11(6):4927-4939. DOI: 10.1039/d0fo00227e. View

2.
Tu J, Brennan M, Wu G, Bai W, Cheng P, Tian B . Delivery of Phenolic Compounds, Peptides and β-Glucan to the Gastrointestinal Tract by Incorporating Dietary Fibre-Rich Mushrooms into Sorghum Biscuits. Foods. 2021; 10(8). PMC: 8391148. DOI: 10.3390/foods10081812. View

3.
Lampitella E, Landi N, Oliva R, Gaglione R, Bosso A, De Lise F . Toxicity and membrane perturbation properties of the ribotoxin-like protein Ageritin. J Biochem. 2021; 170(4):473-482. DOI: 10.1093/jb/mvab062. View

4.
Fraile-Fabero R, Ozcariz-Fermoselle M, Oria-de-Rueda-Salgueiro J, Garcia-Recio V, Cordoba-Diaz D, Del P Jimenez-Lopez M . Differences in Antioxidants, Polyphenols, Protein Digestibility and Nutritional Profile between from Industrial Crops in Asia and from Cultivation and Iberian Origin. Foods. 2021; 10(8). PMC: 8394434. DOI: 10.3390/foods10081750. View

5.
Lee H, Yong H, Kim M, Choi Y, Jo C . Status of meat alternatives and their potential role in the future meat market - A review. Asian-Australas J Anim Sci. 2020; 33(10):1533-1543. PMC: 7463075. DOI: 10.5713/ajas.20.0419. View