Intraoperative Beat-to-Beat Pulse Transit Time (PTT) Monitoring Via Non-Invasive Piezoelectric/Piezocapacitive Peripheral Sensors Can Predict Changes in Invasively Acquired Blood Pressure in High-Risk Surgical Patients

Overview

Journal Sensors (Basel)

Publisher MDPI

Specialty Biotechnology

Date 2023 Mar 30

PMID 36992016

Authors

Michael Nordine

Marius Pille

Jan Kraemer

Christian Berger

Philipp Brandhorst

Philipp Kaeferstein

Roland Kopetsch

Niels Wessel

Ralf Felix Trauzeddel

Sascha Treskatsch

Affiliations

Soon will be listed here.

Abstract

Background: Non-invasive tracking of beat-to-beat pulse transit time (PTT) via piezoelectric/piezocapacitive sensors (PES/PCS) may expand perioperative hemodynamic monitoring. This study evaluated the ability for PTT via PES/PCS to correlate with systolic, diastolic, and mean invasive blood pressure (SBP, DBP, and MAP, respectively) and to detect SBP fluctuations.

Methods: PES/PCS and IBP measurements were performed in 20 patients undergoing abdominal, urological, and cardiac surgery. A Pearson's correlation analysis (r) between 1/PTT and IBP was performed. The predictive ability of 1/PTT with changes in SBP was determined by area under the curve (reported as AUC, sensitivity, specificity).

Results: Significant correlations between 1/PTT and SBP were found for PES (r = 0.64) and PCS (r = 0.55) ( < 0.01), as well as MAP/DBP for PES (r = 0.6/0.55) and PCS (r = 0.5/0.45) ( < 0.05). A 7% decrease in 1/PTT predicted a 30% SBP decrease (0.82, 0.76, 0.76), while a 5.6% increase predicted a 30% SBP increase (0.75, 0.7, 0.68). A 6.6% decrease in 1/PTT detected a 30% SBP decrease (0.81, 0.72, 0.8), while a 4.8% 1/PTT increase detected a 30% SBP increase (0.73, 0.64, 0.68).

Conclusions: Non-invasive beat-to-beat PTT via PES/PCS demonstrated significant correlations with IBP and detected significant changes in SBP. Thus, PES/PCS as a novel sensor technology may augment intraoperative hemodynamic monitoring during major surgery.

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