Microbial Detoxification of Residual Pesticides in Fermented Foods: Current Status and Prospects

Overview

Journal Foods

Specialty Biotechnology

Date 2023 Mar 29

PMID 36981090

Authors

Nadya Armenova

Lidia Tsigoriyna

Alexander Arsov

Kaloyan Petrov

Penka Petrova

Affiliations

Soon will be listed here.

Abstract

The treatment of agricultural areas with pesticides is an indispensable approach to improve crop yields and cannot be avoided in the coming decades. At the same time, significant amounts of pesticides remain in food and their ingestion causes serious damage such as neurological, gastrointestinal, and allergic reactions; cancer; and even death. However, during the fermentation processing of foods, residual amounts of pesticides are significantly reduced thanks to enzymatic degradation by the starter and accompanying microflora. This review concentrates on foods with the highest levels of pesticide residues, such as milk, yogurt, fermented vegetables (pickles, kimchi, and olives), fruit juices, grains, sourdough, and wines. The focus is on the molecular mechanisms of pesticide degradation due to the presence of specific microbial species. They contain a unique genetic pool that confers an appropriate enzymological profile to act as pesticide detoxifiers. The prospects of developing more effective biodetoxification strategies by engaging probiotic lactic acid bacteria are also discussed.

Citing Articles

Bromelia pinguin Extract Mitigates Glyphosate-Induced Toxicity in Human Cells.

Masias-Ambriz L, Caba-Flores M, Montes-Castro N, Garcia-Aguiar I, Ruiz-Ramos R, Zenteno E Cureus. 2025; 16(11):e74701.

PMID: 39741601 PMC: 11685793. DOI: 10.7759/cureus.74701.

Glyphosate as a Food Contaminant: Main Sources, Detection Levels, and Implications for Human and Public Health.

de Morais Valentim J, Coradi C, Viana N, Fagundes T, Micheletti P, Gaboardi S Foods. 2024; 13(11).

PMID: 38890925 PMC: 11171990. DOI: 10.3390/foods13111697.

Engineering Gut Symbionts: A Way to Promote Bee Growth?.

Sattayawat P, Inwongwan S, Noirungsee N, Li J, Guo J, Disayathanoowat T Insects. 2024; 15(5).

PMID: 38786925 PMC: 11121833. DOI: 10.3390/insects15050369.

Pesticides and Polychlorinated Biphenyls in Milk and Dairy Products in Croatia: A Health Risk Assessment.

dokic M, Nekic T, Varenina I, Varga I, Solomun Kolanovic B, Sedak M Foods. 2024; 13(8).

PMID: 38672828 PMC: 11049040. DOI: 10.3390/foods13081155.

Distribution of Pesticides and Polychlorinated Biphenyls in Food of Animal Origin in Croatia.

dokic M, Nekic T, Varenina I, Varga I, Solomun Kolanovic B, Sedak M Foods. 2024; 13(4).

PMID: 38397505 PMC: 10887917. DOI: 10.3390/foods13040528.

References

Shi Y, Zhao X, Zhao J, Zhang H, Zhai Q, Narbad A . A mixture of Lactobacillus species isolated from traditional fermented foods promote recovery from antibiotic-induced intestinal disruption in mice. J Appl Microbiol. 2018; 124(3):842-854. DOI: 10.1111/jam.13687. View

Bose S, Kumar P, Vo D . A review on the microbial degradation of chlorpyrifos and its metabolite TCP. Chemosphere. 2021; 283:131447. DOI: 10.1016/j.chemosphere.2021.131447. View

Cho K, Math R, Asraful Islam S, Lim W, Hong S, Kim J . Biodegradation of chlorpyrifos by lactic acid bacteria during kimchi fermentation. J Agric Food Chem. 2009; 57(5):1882-9. DOI: 10.1021/jf803649z. View

Lu Q, Qiu L, Yu L, Zhang S, de Toledo R, Shim H . Microbial transformation of chiral organohalides: Distribution, microorganisms and mechanisms. J Hazard Mater. 2019; 368:849-861. DOI: 10.1016/j.jhazmat.2019.01.103. View

Heshmati A, Hamidi M, Nili-Ahmadabadi A . Effect of storage, washing, and cooking on the stability of five pesticides in edible fungi of : A degradation kinetic study. Food Sci Nutr. 2020; 7(12):3993-4000. PMC: 6924300. DOI: 10.1002/fsn3.1261. View

Cui Y, Ke R, Gao W, Tian F, Wang Y, Jiang G . Analysis of Organochlorine Pesticide Residues in Various Vegetable Oils Collected in Chinese Markets. J Agric Food Chem. 2020; 68(49):14594-14602. DOI: 10.1021/acs.jafc.0c05227. View

Schleiffer M, Speiser B . Presence of pesticides in the environment, transition into organic food, and implications for quality assurance along the European organic food chain - A review. Environ Pollut. 2022; 313:120116. DOI: 10.1016/j.envpol.2022.120116. View

Gava A, Emer C, Ficagna E, de Andrade S, Fuentefria A . Occurrence and impact of fungicides residues on fermentation during wine production- A review. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021; 38(6):943-961. DOI: 10.1080/19440049.2021.1894357. View

Rezaei F, Nejati R, Sayadi M, Nematollahi A . Diazinon reduction in apple juice using probiotic bacteria during fermentation and storage under refrigeration. Environ Sci Pollut Res Int. 2021; 28(43):61213-61224. DOI: 10.1007/s11356-021-15007-w. View

10.

Li C, Ma Y, Mi Z, Huo R, Zhou T, Hai H . Screening for Strains That Possess Organophosphorus Pesticide-Degrading Activity and Metabolomic Analysis of Phorate Degradation. Front Microbiol. 2018; 9:2048. PMC: 6130228. DOI: 10.3389/fmicb.2018.02048. View

11.

Crowley S, Mahony J, Van Sinderen D . Broad-spectrum antifungal-producing lactic acid bacteria and their application in fruit models. Folia Microbiol (Praha). 2012; 58(4):291-9. DOI: 10.1007/s12223-012-0209-3. View

12.

Bhatt P, Zhou X, Huang Y, Zhang W, Chen S . Characterization of the role of esterases in the biodegradation of organophosphate, carbamate, and pyrethroid pesticides. J Hazard Mater. 2021; 411:125026. DOI: 10.1016/j.jhazmat.2020.125026. View

13.

Ambrus A, Doan V, Szenczi-Cseh J, Szemanne-Dobrik H, Vasarhelyi A . Quality Control of Pesticide Residue Measurements and Evaluation of Their Results. Molecules. 2023; 28(3). PMC: 9920035. DOI: 10.3390/molecules28030954. View

14.

Wu M, Zhang W, Miao J, Sun C, Wang Q, Pan L . Pyrethroids contamination and health risk assessment in seafood collected from the coast of Shandong, China. Mar Pollut Bull. 2022; 186:114442. DOI: 10.1016/j.marpolbul.2022.114442. View

15.

Trinder M, McDowell T, Daisley B, Ali S, Leong H, Sumarah M . Probiotic Lactobacillus rhamnosus Reduces Organophosphate Pesticide Absorption and Toxicity to Drosophila melanogaster. Appl Environ Microbiol. 2016; 82(20):6204-6213. PMC: 5068162. DOI: 10.1128/AEM.01510-16. View

16.

Bogialli S, Curini R, Di Corcia A, Lagana A, Stabile A, Sturchio E . Development of a multiresidue method for analyzing herbicide and fungicide residues in bovine milk based on solid-phase extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2005; 1102(1-2):1-10. DOI: 10.1016/j.chroma.2005.10.011. View

17.

Kovac M, Bulaic M, Jakovljevic J, Nevistic A, Rot T, Kovac T . Mycotoxins, Pesticide Residues, and Heavy Metals Analysis of Croatian Cereals. Microorganisms. 2021; 9(2). PMC: 7909767. DOI: 10.3390/microorganisms9020216. View

18.

Nasreddine L, Parent-Massin D . Food contamination by metals and pesticides in the European Union. Should we worry?. Toxicol Lett. 2002; 127(1-3):29-41. DOI: 10.1016/s0378-4274(01)00480-5. View

19.

Mendez J, Gutierrez-Fernandez A, Hardisson A, Niebla-Canelo D, Alejandro-Vega S, Rubio-Armendariz C . Pesticide Residues in Bananas from the Canary Islands. Foods. 2023; 12(3). PMC: 9914906. DOI: 10.3390/foods12030437. View

20.

Sagratini G, Manes J, Giardina D, Damiani P, Pico Y . Analysis of carbamate and phenylurea pesticide residues in fruit juices by solid-phase microextraction and liquid chromatography-mass spectrometry. J Chromatogr A. 2007; 1147(2):135-43. DOI: 10.1016/j.chroma.2007.02.066. View