Rotational Distortion and Compensation in Optical Coherence Tomography with Anisotropic Pixel Resolution

Overview

Journal Bioengineering (Basel)

Date 2023 Mar 29

PMID 36978706

Authors

Guangying Ma

Taeyoon Son

Tobiloba Adejumo

Xincheng Yao

Affiliations

Soon will be listed here.

Abstract

Accurate image registration is essential for eye movement compensation in optical coherence tomography (OCT) and OCT angiography (OCTA). The spatial resolution of an OCT instrument is typically anisotropic, i.e., has different resolutions in the lateral and axial dimensions. When OCT images have anisotropic pixel resolution, residual distortion (RD) and false translation (FT) are always observed after image registration for rotational movement. In this study, RD and FT were quantitively analyzed over different degrees of rotational movement and various lateral and axial pixel resolution ratio (RL/RA) values. The RD and FT provide the evaluation criteria for image registration. The theoretical analysis confirmed that the RD and FT increase significantly with the rotation degree and RL/RA. An image resizing assisting registration (RAR) strategy was proposed for accurate image registration. The performance of direct registration (DR) and RAR for retinal OCT and OCTA images were quantitatively compared. Experimental results confirmed that unnormalized RL/RA causes RD and FT; RAR can effectively improve the performance of OCT and OCTA image registration and distortion compensation.

Citing Articles

Adaptive vessel tracing and segmentation in OCT enables the robust detection of wall-to-lumen ratio abnormalities in 5xFAD mice.

Adejumo T, Ma G, Son T, Kim T, Le D, Dadzie A Biomed Opt Express. 2024; 14(12):6350-6360.

PMID: 38420326 PMC: 10898580. DOI: 10.1364/BOE.504317.

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