The Evolutionary Cancer Gene Network Theory Versus Embryogenic Hypotheses

Overview

Journal Med Oncol

Publisher Springer

Specialty Oncology

Date 2023 Mar 9

PMID 36892717

Authors

Vladimir Florin Niculescu

Affiliations

Soon will be listed here.

Abstract

The present paper compares the statements of the evolutionary cancer gene-network theory (cancer genome theory) with the statements of embryogenic hypotheses like the embryonic rest hypothesis, the very small embryonic-like stem cells hypothesis, (VSEL), the para-embryonic p-ESC hypothesis, and the PGCC-life cycle hypothesis, including the life code theory. In my opinion, the evolutionary gene network theory is the only theory that can satisfactorily explain the homologies between carcinogenesis, tumorigenesis, metastasis, gametogenesis, and early embryogenesis. From an evolutionary point of view, there is no reason to see the origin of cancer in cells of early embryonic life.

Citing Articles

The evolutionary cancer genome theory and its reasoning.

Niculescu V Genet Med Open. 2024; 1(1):100809.

PMID: 39669240 PMC: 11613669. DOI: 10.1016/j.gimo.2023.100809.

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