Manganese(I)-Catalyzed Asymmetric Hydrophosphination of α,β-Unsaturated Carbonyl Derivatives

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2023 Mar 9

PMID 36892214

Authors

Roxana Postolache

Juana M Perez

Marta Castineira Reis

Luo Ge

Esther G Sinnema

Syuzanna R Harutyunyan

Affiliations

Soon will be listed here.

Abstract

Here we report catalytic asymmetric hydrophosphination of α,β-unsaturated carbonyl derivatives using a chiral Mn(I) complex as a catalyst. Through H-P bond activation, various phosphine-containing chiral products can be accessed via hydrophosphination of various ketone-, ester-, and carboxamide-based Michael acceptors.

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