Neurogenic Rosacea Could Be a Small Fiber Neuropathy

Overview

Journal Front Pain Res (Lausanne)

Date 2023 Mar 9

PMID 36890854

Authors

Min Li

Meng Tao

Yue Zhang

Ruoxin Pan

Duoduo Gu

Yang Xu

Affiliations

Soon will be listed here.

Citing Articles

Managing a Burning Face: Clinical Manifestations and Therapeutic Approaches for Neurogenic Rosacea.

Aedo G, Chahuan M, Gatica E, Herrera I, Parada L, Seguel A Int J Mol Sci. 2025; 26(5).

PMID: 40076987 PMC: 11901027. DOI: 10.3390/ijms26052366.

Efficacy of Treatments in Reducing Facial Erythema in Rosacea: A Systematic Review.

Hua N, Chen J, Geng R, Sibbald R, Sibbald C J Cutan Med Surg. 2024; 29(1):43-50.

PMID: 39478371 PMC: 11829502. DOI: 10.1177/12034754241287546.

Therapeutic strategies focusing on immune dysregulation and neuroinflammation in rosacea.

Tu K, Jung C, Shih Y, Chang A Front Immunol. 2024; 15:1403798.

PMID: 39136023 PMC: 11317294. DOI: 10.3389/fimmu.2024.1403798.

The role of macrophages in rosacea: implications for targeted therapies.

Liu Y, Zhou Y, Chu C, Jiang X Front Immunol. 2023; 14:1211953.

PMID: 37691916 PMC: 10484341. DOI: 10.3389/fimmu.2023.1211953.

References

Brenaut E, Marcorelles P, Genestet S, Menard D, Misery L . Pruritus: an underrecognized symptom of small-fiber neuropathies. J Am Acad Dermatol. 2014; 72(2):328-32. DOI: 10.1016/j.jaad.2014.10.034. View

Choi J, Di Nardo A . Skin neurogenic inflammation. Semin Immunopathol. 2018; 40(3):249-259. PMC: 6047518. DOI: 10.1007/s00281-018-0675-z. View

Kim H, Kang S, Kim K, Cho S, Kim K, Kim I . Neurogenic rosacea in Korea. J Dermatol. 2020; 48(1):49-55. DOI: 10.1111/1346-8138.15629. View

Lonne-Rahm S, Nordlind K, Wiegleb Edstrom D, Ros A, Berg M . Laser treatment of rosacea: a pathoetiological study. Arch Dermatol. 2004; 140(11):1345-9. DOI: 10.1001/archderm.140.11.1345. View

de Greef B, Hoeijmakers J, Gorissen-Brouwers C, Geerts M, Faber C, Merkies I . Associated conditions in small fiber neuropathy - a large cohort study and review of the literature. Eur J Neurol. 2017; 25(2):348-355. PMC: 5814938. DOI: 10.1111/ene.13508. View

Buddenkotte J, Steinhoff M . Recent advances in understanding and managing rosacea. F1000Res. 2019; 7. PMC: 6281021. DOI: 10.12688/f1000research.16537.1. View

Wienholtz N, Thyssen J, Christensen C, Thomsen S, Karmisholt K, Jemec G . Validity and reliability of the Rosacea Area and Severity Index: A novel scoring system for clinical assessment of rosacea severity. J Eur Acad Dermatol Venereol. 2022; 37(3):573-580. DOI: 10.1111/jdv.18721. View

Scharschmidt T, Yost J, Truong S, Steinhoff M, Wang K, Berger T . Neurogenic rosacea: a distinct clinical subtype requiring a modified approach to treatment. Arch Dermatol. 2011; 147(1):123-6. PMC: 3692271. DOI: 10.1001/archdermatol.2010.413. View

Huet F, Dion A, Batardiere A, Nedelec A, Le Caer F, Bourgeois P . Sensitive skin can be small fibre neuropathy: results from a case-control quantitative sensory testing study. Br J Dermatol. 2018; 179(5):1157-1162. DOI: 10.1111/bjd.17082. View

10.

Sene D . Small fiber neuropathy: Diagnosis, causes, and treatment. Joint Bone Spine. 2017; 85(5):553-559. DOI: 10.1016/j.jbspin.2017.11.002. View

11.

Bucher F, Schneider C, Blau T, Cursiefen C, Fink G, Lehmann H . Small-Fiber Neuropathy Is Associated With Corneal Nerve and Dendritic Cell Alterations: An In Vivo Confocal Microscopy Study. Cornea. 2015; 34(9):1114-9. DOI: 10.1097/ICO.0000000000000535. View

12.

Egeberg A, Weinstock L, Thyssen E, Gislason G, Thyssen J . Rosacea and gastrointestinal disorders: a population-based cohort study. Br J Dermatol. 2016; 176(1):100-106. DOI: 10.1111/bjd.14930. View

13.

Guzman-Sanchez D, Ishiuji Y, Patel T, Fountain J, Chan Y, Yosipovitch G . Enhanced skin blood flow and sensitivity to noxious heat stimuli in papulopustular rosacea. J Am Acad Dermatol. 2007; 57(5):800-5. DOI: 10.1016/j.jaad.2007.06.009. View

14.

Zhang Y, Li Y, Zhou L, Yuan X, Wang Y, Deng Q . Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases. Redox Biol. 2022; 55:102427. PMC: 9372634. DOI: 10.1016/j.redox.2022.102427. View

15.

Oussedik E, Bourcier M, Tan J . Psychosocial Burden and Other Impacts of Rosacea on Patients' Quality of Life. Dermatol Clin. 2018; 36(2):103-113. DOI: 10.1016/j.det.2017.11.005. View

16.

Hoeijmakers J, Faber C, Lauria G, Merkies I, Waxman S . Small-fibre neuropathies--advances in diagnosis, pathophysiology and management. Nat Rev Neurol. 2012; 8(7):369-79. DOI: 10.1038/nrneurol.2012.97. View

17.

Schram A, James W . Neurogenic rosacea treated with endoscopic thoracic sympathectomy. Arch Dermatol. 2012; 148(2):270-1. DOI: 10.1001/archdermatol.2011.2615. View