Bibliometric Insights in Fournier's Gangrene: Research Landscapes, Turning Points, and Global Trends

Overview

Journal Front Surg

Specialty General Surgery

Date 2023 Mar 6

PMID 36874468

Authors

Jia-Yuan Zhang

Chang-Fang Xiao

Chen Wang

Yi-Bo Yao

Affiliations

Soon will be listed here.

Abstract

Study Design: Bibliometric and visualization analysis.

Objective: To analyze the research landscapes and hotspots of Fournier's gangrene, and reveal the dynamic changes and development trend of research hotspots for the purpose of providing ideas and a basis for clinical and basic research in this field.

Methods: Research datasets were acquired from the Web of Science. The publication years were limited from January 1, 1900 to August 5, 2022. The bibliometric tools CiteSpace (v5.8) and VOSviewer (v1.6) were used to analyze the data and generate visualization knowledge maps. Trends in annual publications, distribution, H-index status, coauthorships status and research hotspots were analyzed.

Results: According to the search strategy, we identified and enrolled 688 publications regarding to Fournier's gangrene. The number of published papers showed an overall upwards trend. The USA was the largest contributor, ranking first in total publications, citations and the H-index. The top 10 most productive institutions were all from the USA. De Simone B and Sartelli M were the most productive authors. There was close cooperation among countries, but the cooperation among institutions and authors had little contact and poor interactivity. The research hotspots included the pathogenesis factors and treatment. All the identified keywords were divided into 14 clusters, and the label of the latest cluster was "empagliflozin". Prognosis and risk factors, emerging treatment methods, and pathogenesis were at the forefront of the Fournier's gangrene field and were predicted to be the next hot topics.

Conclusion: The research of Fournier's gangrene has made some achievements, but the overall research level is still in the primary stage. The academic cooperation between different institutions and authors needs to be strengthened. At the early stage, the mainstream of research was the infected tissue and site, pathogenesis, and diagnosis of disease, while research on newly discovered sodium-glucose cotransporter 2 inhibitor, adjuvant therapy and prognostic factors may be the main directions in the future.

Citing Articles

Comprehensive Analysis of the Biomechanical Research of Pelvic Organ Prolapse: A Scientometric Approach.

Du H, Yang M, Qi X, Yang L, Wang Z, Yang T J Multidiscip Healthc. 2025; 18:1249-1268.

PMID: 40046658 PMC: 11881611. DOI: 10.2147/JMDH.S473196.

Comprehensive management and outcomes in female patients with Fournier's gangrene: A case report.

El Hajjar C, Al Hassan J, Siblini M, Madi N, Abou Hammin S, Nakib H SAGE Open Med Case Rep. 2024; 12:2050313X241271829.

PMID: 39157030 PMC: 11329950. DOI: 10.1177/2050313X241271829.

Bibliometric and Visualization Analysis of Biomechanical Research on Lumbar Intervertebral Disc.

Hou Z, Wang W, Su S, Chen Y, Chen L, Lu Y J Pain Res. 2023; 16:3441-3462.

PMID: 37869478 PMC: 10590139. DOI: 10.2147/JPR.S428991.

Research hotspots and trends of brain-computer interface technology in stroke: a bibliometric study and visualization analysis.

Li F, Zhang D, Chen J, Tang K, Li X, Hou Z Front Neurosci. 2023; 17:1243151.

PMID: 37732305 PMC: 10507647. DOI: 10.3389/fnins.2023.1243151.

References

Dave C, Schneeweiss S, Patorno E . Comparative risk of genital infections associated with sodium-glucose co-transporter-2 inhibitors. Diabetes Obes Metab. 2018; 21(2):434-438. PMC: 6329650. DOI: 10.1111/dom.13531. View

Del Zingaro M, Boni A, Paladini A, Rossi de Vermandois J, Ciarletti S, Felici G . Fournier's gangrene secondary to locally advanced prostate cancer: case report and review of the Literature. G Chir. 2020; 40(6):481-496. View

Lu C, Liu M, Shang W, Yuan Y, Li M, Deng X . Knowledge Mapping of (Danggui) Research: A Scientometric Study. Front Pharmacol. 2020; 11:294. PMC: 7082756. DOI: 10.3389/fphar.2020.00294. View

Franco-Buenaventura D, Garcia-Perdomo H . Vacuum-assisted closure device in the postoperative wound care for Fournier's gangrene: a systematic review. Int Urol Nephrol. 2020; 53(4):641-653. DOI: 10.1007/s11255-020-02705-6. View

Chennamsetty A, Khourdaji I, Burks F, Killinger K . Contemporary diagnosis and management of Fournier's gangrene. Ther Adv Urol. 2015; 7(4):203-15. PMC: 4580094. DOI: 10.1177/1756287215584740. View

V K, Hiremath B, V A I . Necrotising soft tissue infection-risk factors for mortality. J Clin Diagn Res. 2013; 7(8):1662-5. PMC: 3782925. DOI: 10.7860/JCDR/2013/5535.3240. View

Singh A, Ahmed K, Aydin A, Khan M, Dasgupta P . Fournier's gangrene. A clinical review. Arch Ital Urol Androl. 2016; 88(3):157-164. DOI: 10.4081/aiua.2016.3.157. View

Ulug M, Gedik E, Girgin S, Celen M, Ayaz C . The evaluation of microbiology and Fournier's gangrene severity index in 27 patients. Int J Infect Dis. 2009; 13(6):e424-30. DOI: 10.1016/j.ijid.2009.01.021. View

Montrief T, Long B, Koyfman A, Auerbach J . Fournier Gangrene: A Review for Emergency Clinicians. J Emerg Med. 2019; 57(4):488-500. DOI: 10.1016/j.jemermed.2019.06.023. View

10.

Roghmann F, von Bodman C, Loppenberg B, Hinkel A, Palisaar J, Noldus J . Is there a need for the Fournier's gangrene severity index? Comparison of scoring systems for outcome prediction in patients with Fournier's gangrene. BJU Int. 2012; 110(9):1359-65. DOI: 10.1111/j.1464-410X.2012.11082.x. View

11.

Hatipoglu E, Demiryas S, Simsek O, Saribeyoglu K, Pekmezci S . Fournier's gangrene: Five years' experience from a single center in Turkey. Ulus Travma Acil Cerrahi Derg. 2020; 26(2):235-241. DOI: 10.14744/tjtes.2020.66805. View

12.

Sorensen M, Krieger J, Rivara F, Broghammer J, Klein M, Mack C . Fournier's Gangrene: population based epidemiology and outcomes. J Urol. 2009; 181(5):2120-6. PMC: 3042351. DOI: 10.1016/j.juro.2009.01.034. View

13.

Garcia Morua A, Lopez J, Gutierrez Garcia J, Martinez Montelongo R, Gomez Guerra L . Fournier's gangrene: our experience in 5 years, bibliographic review and assessment of the Fournier's gangrene severity index. Arch Esp Urol. 2009; 62(7):532-40. View

14.

Shyam D, Rapsang A . Fournier's gangrene. Surgeon. 2013; 11(4):222-32. DOI: 10.1016/j.surge.2013.02.001. View

15.

Ngugi P, Magoha G, Nyaga P . Fournier's ganrene in the HIV era. Afr Health Sci. 2015; 14(4):1063-8. PMC: 4370088. DOI: 10.4314/ahs.v14i4.38. View

16.

Ureyen O, Acar A, Gokcelli U, Atahan M, Ilhan E . Usefulness of FGSI and UFGSI scoring systems for predicting mortality in patients with Fournier's gangrene: A multicenter study. Ulus Travma Acil Cerrahi Derg. 2017; 23(5):389-394. DOI: 10.5505/tjtes.2017.71509. View

17.

Synnestvedt M, Chen C, Holmes J . CiteSpace II: visualization and knowledge discovery in bibliographic databases. AMIA Annu Symp Proc. 2006; :724-8. PMC: 1560567. View

18.

Ong H, Ho Y . Genitoperineal gangrene: experience in Singapore. Aust N Z J Surg. 1996; 66(5):291-3. DOI: 10.1111/j.1445-2197.1996.tb01188.x. View

19.

Soh C, Pietrobon R, Freiberger J, Chew S, Rajgor D, Gandhi M . Hyperbaric oxygen therapy in necrotising soft tissue infections: a study of patients in the United States Nationwide Inpatient Sample. Intensive Care Med. 2012; 38(7):1143-51. DOI: 10.1007/s00134-012-2558-4. View

20.

Yu P, Sanger J, Matloub H, Gosain A, Larson D . Anterolateral thigh fasciocutaneous island flaps in perineoscrotal reconstruction. Plast Reconstr Surg. 2002; 109(2):610-6; discussion 617-8. DOI: 10.1097/00006534-200202000-00030. View