Study to Evaluate the Relation Between Weight Gain in Infants and Occurrence of Retinopathy of Prematurity

Overview

Journal Indian J Ophthalmol

Specialty Ophthalmology

Date 2023 Mar 6

PMID 36872704

Authors

Neha K Sethi

Barkha Jain

Natha Ram Gupta

Surinder Pal Singh

Gurmeet Sethi

Charu Chadha

Affiliations

Soon will be listed here.

Abstract

Purpose: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. Capturing serial daily postnatal weight gain can act as an innovative, low-cost method of risk stratification. We aim to study the relation between weight gain in infants and occurrence of ROP.

Methods: The prospective, observational study was conducted on 62 infants. ROP screening was done based on the Rashtriya Bal Swasthya Karyakram (RBSK) criteria. Infants were classified into no ROP (n = 28), mild ROP (n = 8), and treatable ROP (n = 26) groups. Average daily postnatal weight gain was measured and its relation to development of ROP was studied. All statistical calculations were done using Statistical Package for the Social Sciences (SPSS) 21 version (SPSS Inc., Chicago, IL, USA) statistical program for Microsoft Windows.

Results: Mean rate of weight gain in no ROP group, mild ROP group, and treatable ROP group was 33.12, 27.19, and 15.31 g/day, respectively (P = 0.001). Mean gestational age and birth weight in treatable group (n = 26) were 31.38 weeks and 1572.31 g, respectively. Receiver operating curve analysis revealed a cutoff of 29.33 g/day for ROP and 21.91 g/day for severe ROP.

Conclusion: We concluded that, babies with poor weight gain of below 29.33 g/day are at high risk for ROP and babies with wight gain of 21.91 g/day are at high risk for severe ROP. These babies should be followed meticulously. So, the rate of weight gain of a preterm can help us to prioritize babies.

Citing Articles

Clinical and Growth Correlates of Retinopathy of Prematurity in Preterm Infants with Surgical Necrotizing Enterocolitis and Intestinal Perforation.

Garg P, Riddick R, Ansari M, Meilstrup A, Zepponi D, Smith A Am J Perinatol. 2024; 41(15):2152-2164.

PMID: 38565196 PMC: 11496023. DOI: 10.1055/a-2297-8644.

Usefulness of Children's Hospital of Philadelphia ROP (CHOP ROP) model in the prediction of type 1 ROP.

Jain B, Sethi N, Sethi A, Arora R, Gupta T, Kaur H Indian J Ophthalmol. 2023; 71(11):3473-3477.

PMID: 37870009 PMC: 10752303. DOI: 10.4103/IJO.IJO_415_23.

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