The Wound Healing Potential of and Other Ethno-myco Wound Healing Agents

Overview

Journal Mycobiology

Date 2023 Feb 27

PMID 36846625

Authors

Hui-Yeng Y Yap

Mohammad Farhan Ariffeen Rosli

Soon-Hao Tan

Boon-Hong Kong

Shin-Yee Fung

Affiliations

Soon will be listed here.

Abstract

Wound care has become increasingly important over the years. Various synthetic products for wound care treatment have been reported to cause toxic side effects and therefore natural products are in significant demand as they have minimal side effects. The presence of bioactive compounds in medicinal mushrooms contributes to various biological activities which assist in the early inflammatory phase, keratinocyte proliferation, and its migration enhancement which are pertinent to wound rehabilitation. (tiger milk mushroom) can reduce the inflammation phase in wound healing by fighting off bacterial infection and modulating pro-inflammatory cytokines expression in the early stage to avoid prolonged inflammation and tissue damage. The antibacterial, immunomodulating, and anti-inflammatory activities exhibited by most macrofungi play a key role in enhancing wound healing. Several antibacterial and antifungal compounds sourced from traditional botanicals/products may prevent further complications and reoccurrence of injury to a wounded site. Scientific studies are actively underway to ascertain the potential use of macrofungi as a wound healing agent.

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