Study on the Association Between Gene InDel and Sheep Body Conformation Traits

Overview

Journal Genes (Basel)

Publisher MDPI

Date 2023 Feb 25

PMID 36833283

Authors

Jiaqiang Zhang

Zhansaya Toremurat

Yilin Liang

Jie Cheng

Zhenzhen Sun

Yangming Huang

Junxia Liu

Buren Chaogetu

Gang Ren

Hong Chen

Affiliations

Soon will be listed here.

Abstract

Marker-assisted selection is an important method for livestock breeding. In recent years, this technology has been gradually applied to livestock breeding to improve the body conformation traits. In this study, the (Leucine Rich Repeat Containing 8 VRAC Subunit B) gene was selected to evaluate the association between its genetic variations and the body conformation traits in two native sheep breeds in China. Four body conformation traits, including withers height, body length, chest circumference, and body weight, were collected from 269 Chaka sheep. We also collected the body length, chest width, withers height, chest depth, chest circumference, cannon bone circumference, and height at hip cross of 149 Small-Tailed Han sheep. Two different genotypes, ID and DD, were detected in all sheep. Our data showed that the polymorphism of the gene was significantly associated with chest depth ( < 0.05) in Small-Tailed Han sheep, and it is greater in sheep with DD than those with ID. In conclusion, our data suggested that the gene could serve as a candidate gene for marker-assisted selection in Small-Tailed Han sheep.

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