» Articles » PMID: 36819756

The CuO and AgO Co-modified ZnO Nanocomposites for Promoting Wound Healing in Infection

Overview
Journal Mater Today Bio
Date 2023 Feb 23
PMID 36819756
Authors
Affiliations
Soon will be listed here.
Abstract

Bacterial has become a common pathogen of humans owing to their drug-resistant effects and evasion of the host immune system, with their ability to form biofilm and induce severe infections, a condition which has become a primary public health concern globally. Herein, we report on CuO@AgO/ZnO NPs antibacterial activity enhanced by near-infrared (NIR) light which was effective in the elimination of and the . The CuO@AgO/ZnO NPs under NIR significantly eradicated and its biofilm and , and subsequently exhibited such phenomenon , eliminating bacteria and healing wound. This demonstrated the combined intrinsic antibacterial potency of the Cu and Ag components of the CuO@AgO/ZnO NPs was enhanced tremendously to achieve such outcomes in and . Considering the above advantages and facile preparation methods, the CuO@AgO/ZnO NPs synthesized in this work may prove as an important antibacterial agent in bacterial-related infection therapeutics and for biomedical-related purposes.

Citing Articles

Electrospun Nanofibers for the Delivery of Endolysin/Dendronized Ag-NPs Complex Against Pseudomonas aeruginosa.

Lasak M, Lysek-Gladysinska M, Lach K, Nirwan V, Kuc-Ciepluch D, Sanchez-Nieves J Nanotechnol Sci Appl. 2025; 18:57-70.

PMID: 39989599 PMC: 11846615. DOI: 10.2147/NSA.S498942.


Engineering dual-driven pro-angiogenic nanozyme based on porous silicon for synergistic acceleration of burn infected wound healing.

Duan W, Gao Y, Xu R, Huang S, Xia X, Zhao J Mater Today Bio. 2025; 31:101522.

PMID: 39935892 PMC: 11810849. DOI: 10.1016/j.mtbio.2025.101522.


In situ forming Hydrogel with adding ZnO Nano-particle for effectively methicillin-resistant Staphylococcus aureus infected frostbite injury.

Xu X, Wang J, Sun T, Li Q, Ning R Regen Ther. 2024; 26:956-966.

PMID: 39512738 PMC: 11541235. DOI: 10.1016/j.reth.2024.10.008.


Exploring nanobioceramics in wound healing as effective and economical alternatives.

Al-Naymi H, Al-Musawi M, Mirhaj M, Valizadeh H, Momeni A, Danesh Pajooh A Heliyon. 2024; 10(19):e38497.

PMID: 39391491 PMC: 11466581. DOI: 10.1016/j.heliyon.2024.e38497.


Antibiotic Nanoparticles-Loaded Wound Dressings Against 's Skin Infection: A Systematic Review.

Quinones-Vico M, Ubago-Rodriguez A, Fernandez-Gonzalez A, Sanabria-de la Torre R, Sierra-Sanchez A, Montero-Vilchez T Int J Nanomedicine. 2024; 19():7895-7926.

PMID: 39108405 PMC: 11302427. DOI: 10.2147/IJN.S469724.


References
1.
Vincent M, Duval R, Hartemann P, Engels-Deutsch M . Contact killing and antimicrobial properties of copper. J Appl Microbiol. 2017; 124(5):1032-1046. DOI: 10.1111/jam.13681. View

2.
Barki K, Das A, Dixith S, Ghatak P, Mathew-Steiner S, Schwab E . Electric Field Based Dressing Disrupts Mixed-Species Bacterial Biofilm Infection and Restores Functional Wound Healing. Ann Surg. 2017; 269(4):756-766. PMC: 6568008. DOI: 10.1097/SLA.0000000000002504. View

3.
Hu D, Li H, Wang B, Ye Z, Lei W, Jia F . Surface-Adaptive Gold Nanoparticles with Effective Adherence and Enhanced Photothermal Ablation of Methicillin-Resistant Staphylococcus aureus Biofilm. ACS Nano. 2017; 11(9):9330-9339. DOI: 10.1021/acsnano.7b04731. View

4.
Zhang L, Gao S, Zhang F, Yang K, Ma Q, Zhu L . Activatable hyaluronic acid nanoparticle as a theranostic agent for optical/photoacoustic image-guided photothermal therapy. ACS Nano. 2014; 8(12):12250-8. DOI: 10.1021/nn506130t. View

5.
Shao W, Liu X, Min H, Dong G, Feng Q, Zuo S . Preparation, characterization, and antibacterial activity of silver nanoparticle-decorated graphene oxide nanocomposite. ACS Appl Mater Interfaces. 2015; 7(12):6966-73. DOI: 10.1021/acsami.5b00937. View