Nanotheranostics-based Management of Head and Neck Cancer

Overview

Journal Nanotheranostics

Specialty Biotechnology

Date 2023 Feb 16

PMID 36793352

Authors

Vivek P Chavda

Pankti C Balar

Srushti B Patel

Affiliations

Soon will be listed here.

Abstract

Head and neck cancer is affecting a large sort of population. Many treatments are available on a regular base, but they have their limitations. Diagnosis in the early stage is essential to cope with the disease which is a limitation in the majority of present diagnostic tools. Many of them are invasive methods that lead to patient discomfort. Interventional nanothernostics is an emerging field in the management of Head and Neck cancer. It facilitates both diagnostic and therapeutic approaches. It also helps with the overall management of the disease. This method allows the early and accurate detection of the disease which improvises the chances of recovery. Additionally, it makes sure that the medicine is delivered specifically to increase clinical outcomes and reduce side effects. The use of radiation in addition to the medicine supplied can produce a synergistic effect. It contains several nanoparticles, including silicon and gold nanoparticles. This review paper focuses on the shortcomings of existing therapeutic techniques and how nanotheranostics fills the void.

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References

Nelke K, Pawlak W, Leszczyszyn J, Gerber H . Photodynamic therapy in head and neck cancer. Postepy Hig Med Dosw (Online). 2014; 68:119-28. DOI: 10.5604/17322693.1088044. View

Gavas S, Quazi S, Karpinski T . Nanoparticles for Cancer Therapy: Current Progress and Challenges. Nanoscale Res Lett. 2021; 16(1):173. PMC: 8645667. DOI: 10.1186/s11671-021-03628-6. View

Kim J, Leeman J, Riaz N, McBride S, Tsai C, Lee N . Proton Therapy for Head and Neck Cancer. Curr Treat Options Oncol. 2018; 19(6):28. DOI: 10.1007/s11864-018-0546-9. View

Her S, Jaffray D, Allen C . Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements. Adv Drug Deliv Rev. 2015; 109:84-101. DOI: 10.1016/j.addr.2015.12.012. View

Schmidt H, Kulasinghe A, Kenny L, Punyadeera C . The development of a liquid biopsy for head and neck cancers. Oral Oncol. 2016; 61:8-11. DOI: 10.1016/j.oraloncology.2016.07.014. View

Makitie A, Almangush A, Youssef O, Metsala M, Silen S, Nixon I . Exhaled breath analysis in the diagnosis of head and neck cancer. Head Neck. 2019; 42(4):787-793. DOI: 10.1002/hed.26043. View

Wilczewska A, Niemirowicz K, Markiewicz K, Car H . Nanoparticles as drug delivery systems. Pharmacol Rep. 2012; 64(5):1020-37. DOI: 10.1016/s1734-1140(12)70901-5. View

Yu C, Li L, Wang S, Xu Y, Wang L, Huang Y . Advances in nanomaterials for the diagnosis and treatment of head and neck cancers: A review. Bioact Mater. 2023; 25:430-444. PMC: 10087112. DOI: 10.1016/j.bioactmat.2022.08.010. View

Guo K, Xiao W, Chen X, Zhao Z, Lin Y, Chen G . Epidemiological Trends of Head and Neck Cancer: A Population-Based Study. Biomed Res Int. 2021; 2021:1738932. PMC: 8294963. DOI: 10.1155/2021/1738932. View

10.

Master A, Livingston M, Sen Gupta A . Photodynamic nanomedicine in the treatment of solid tumors: perspectives and challenges. J Control Release. 2013; 168(1):88-102. PMC: 3780355. DOI: 10.1016/j.jconrel.2013.02.020. View

11.

Lambert R, Sauvaget C, de Camargo Cancela M, Sankaranarayanan R . Epidemiology of cancer from the oral cavity and oropharynx. Eur J Gastroenterol Hepatol. 2011; 23(8):633-41. DOI: 10.1097/MEG.0b013e3283484795. View

12.

Bertrand N, Wu J, Xu X, Kamaly N, Farokhzad O . Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv Drug Deliv Rev. 2013; 66:2-25. PMC: 4219254. DOI: 10.1016/j.addr.2013.11.009. View

13.

Plavc G, Jesenko T, Orazem M, Strojan P . Challenges in Combining Immunotherapy with Radiotherapy in Recurrent/Metastatic Head and Neck Cancer. Cancers (Basel). 2020; 12(11). PMC: 7692120. DOI: 10.3390/cancers12113197. View

14.

Dharmawardana N, Woods C, Watson D, Yazbeck R, Ooi E . A review of breath analysis techniques in head and neck cancer. Oral Oncol. 2020; 104:104654. DOI: 10.1016/j.oraloncology.2020.104654. View

15.

Bazak R, Houri M, El Achy S, Hussein W, Refaat T . Passive targeting of nanoparticles to cancer: A comprehensive review of the literature. Mol Clin Oncol. 2014; 2(6):904-908. PMC: 4179822. DOI: 10.3892/mco.2014.356. View

16.

Siegel R, Miller K, Jemal A . Cancer statistics, 2018. CA Cancer J Clin. 2018; 68(1):7-30. DOI: 10.3322/caac.21442. View

17.

Siegel R, Miller K, Jemal A . Cancer statistics, 2019. CA Cancer J Clin. 2019; 69(1):7-34. DOI: 10.3322/caac.21551. View

18.

Tinhofer I, Braunholz D, Klinghammer K . Preclinical models of head and neck squamous cell carcinoma for a basic understanding of cancer biology and its translation into efficient therapies. Cancers Head Neck. 2020; 5:9. PMC: 7376675. DOI: 10.1186/s41199-020-00056-4. View

19.

Xie F, Wang M, Chen Q, Chi T, Zhu S, Wei P . Endogenous stimuli-responsive nanoparticles for cancer therapy: From bench to bedside. Pharmacol Res. 2022; 186:106522. DOI: 10.1016/j.phrs.2022.106522. View

20.

El-Sayed I . Nanotechnology in head and neck cancer: the race is on. Curr Oncol Rep. 2010; 12(2):121-8. PMC: 2842561. DOI: 10.1007/s11912-010-0087-2. View