» Articles » PMID: 37151802

Current Status of Cancer Nanotheranostics: Emerging Strategies for Cancer Management

Overview
Specialty Biotechnology
Date 2023 May 8
PMID 37151802
Authors
Affiliations
Soon will be listed here.
Abstract

Cancer diagnosis and management have been a slow-evolving area in medical science. Conventional therapies have by far proved to have various limitations. Also, the concept of immunotherapy which was thought to revolutionize the management of cancer has presented its range of drawbacks. To overcome these limitations nanoparticulate-derived diagnostic and therapeutic strategies are emerging. These nanomaterials are to be explored as they serve as a prospect for cancer theranostics. Nanoparticles have a significant yet unclear role in screening as well as therapy of cancer. However, nanogels and Photodynamic therapy is one such approach to be developed in cancer theranostics. Photoactive cancer theranostics is a vivid area that might prove to help manage cancer. Also, the utilization of the quantum dots as a diagnostic tool and to selectively kill cancer cells, especially in CNS tumors. Additionally, the redox-sensitive micelles targeting the tumor microenvironment of the cancer are also an important theranostic tool. This review focuses on exploring various agents that are currently being studied or can further be studied as cancer theranostics.

Citing Articles

Lipid-Based Nanocarriers: Bridging Diagnosis and Cancer Therapy.

Giordano A, Provenza A, Reverchon G, Baldino L, Reverchon E Pharmaceutics. 2024; 16(9).

PMID: 39339195 PMC: 11434863. DOI: 10.3390/pharmaceutics16091158.


Gold Nanoparticles Downregulate IL-6 Expression/Production by Upregulating microRNA-26a-5p and Deactivating the RelA and NF-κBp50 Transcription Pathways in Activated Breast Cancer Cells.

Farhana A, Alsrhani A, Alghsham R, Derafa W, Khan Y, Rasheed Z Int J Mol Sci. 2024; 25(3).

PMID: 38338683 PMC: 10855246. DOI: 10.3390/ijms25031404.


Nanotheranostics: The Fabrication of Theranostics with Nanoparticles and their Application to Treat the Neurological Disorders.

Singh A, Patel A, Chaudhary H, Yadav K, Minocha N Recent Pat Nanotechnol. 2023; 19(1):17-34.

PMID: 37464820 DOI: 10.2174/1872210517666230718115651.

References
1.
Liu Y, Bhattarai P, Dai Z, Chen X . Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer. Chem Soc Rev. 2018; 48(7):2053-2108. PMC: 6437026. DOI: 10.1039/c8cs00618k. View

2.
Chavda V, Soni S, Vora L, Soni S, Khadela A, Ajabiya J . mRNA-Based Vaccines and Therapeutics for COVID-19 and Future Pandemics. Vaccines (Basel). 2022; 10(12). PMC: 9785933. DOI: 10.3390/vaccines10122150. View

3.
Song J, Yang X, Jacobson O, Lin L, Huang P, Niu G . Sequential Drug Release and Enhanced Photothermal and Photoacoustic Effect of Hybrid Reduced Graphene Oxide-Loaded Ultrasmall Gold Nanorod Vesicles for Cancer Therapy. ACS Nano. 2015; 9(9):9199-209. PMC: 5227595. DOI: 10.1021/acsnano.5b03804. View

4.
Pelaz B, Alexiou C, Alvarez-Puebla R, Alves F, Andrews A, Ashraf S . Diverse Applications of Nanomedicine. ACS Nano. 2017; 11(3):2313-2381. PMC: 5371978. DOI: 10.1021/acsnano.6b06040. View

5.
Kundu P, Singh D, Singh A, Sahoo S . Cancer Nanotheranostics: A Nanomedicinal Approach for Cancer Therapy and Diagnosis. Anticancer Agents Med Chem. 2019; 20(11):1288-1299. DOI: 10.2174/1871520619666190820145930. View