Burning Mouth Syndrome and Hypertension: Prevalence, Gender Differences and Association with Pain and Psycho-Social Characteristics-A Case Control Study

Overview

Journal Int J Environ Res Public Health

Publisher MDPI

Specialties Environmental Health
Public Health

Date 2023 Feb 11

PMID 36767407

Authors

Daniela Adamo

Federica Canfora

Elena Calabria

Noemi Coppola

Mattia Sansone

Gianrico Spagnuolo

Giuseppe Pecoraro

Massimo Aria

Luca DAniello

Michele Davide Mignogna

Stefania Leuci

Affiliations

Soon will be listed here.

Abstract

Background: To assess the prevalence of hypertension (HTN) in burning mouth syndrome (BMS) patients and to investigate its relationship with sociodemographic factors, pain and the psychological profile.

Methods: A case-control study was conducted by enrolling 242 BMS patients and 242 controls matched for age and gender. Sociodemographic and clinical characteristics were recorded, and all participants completed numeric rating scale (NRS), the short-form of the McGill pain questionnaire (SF-MPQ), the Hamilton rating scale for anxiety and depression (HAM-A, HAM-D), the Pittsburgh sleep quality index (PSQI) and the Epworth sleepiness scale (ESS).

Results: The BMS patients presented with a statistically significant higher prevalence of HTN compared to that in the controls (55% versus 33.5%; -value: <0.001) and higher median scores of the NRS, SF-MPQ, HAM-A, HAM-D, PSQI and ESS ( < 0.001). Multivariate regression analysis in the BMS patients indicated positive correlations between HTN and age, systemic diseases, drug consumption and anxiety (-value: <0.001) and these predictors were responsible for 11.3% of the HTN variance in the BMS patients, when considered together.

Conclusions: The prevalence of HTN was significantly higher in the BMS patients, since ageing, the presence of comorbidities, drug consumption and anxiety were potential predictors. Further studies are needed to better investigate the relationship between BMS and HTN.

Citing Articles

Gender differences in pain perception among burning mouth syndrome patients: a cross-sectional study of 242 men and 242 women.

Calabria E, Canfora F, Leuci S, Coppola N, Pecoraro G, Giudice A Sci Rep. 2024; 14(1):3340.

PMID: 38336850 PMC: 10858236. DOI: 10.1038/s41598-024-53074-4.

Non-Communicable Diseases and Associated Risk Factors in Burning Mouth Syndrome Patients.

Parlatescu I, Dugan C, Popescu B, Tovaru S, Dobre M, Milanesi E Medicina (Kaunas). 2023; 59(12).

PMID: 38138188 PMC: 10744480. DOI: 10.3390/medicina59122085.

Advancements in Understanding and Classifying Chronic Orofacial Pain: Key Insights from Biopsychosocial Models and International Classifications (ICHD-3, ICD-11, ICOP).

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Unraveling the link between hypertension and depression in older adults: a meta-analysis.

Gan Q, Yu R, Lian Z, Yuan Y, Li Y, Zheng L Front Public Health. 2023; 11:1302341.

PMID: 38074728 PMC: 10704466. DOI: 10.3389/fpubh.2023.1302341.

Chronic orofacial pain and white matter hyperintensities.

Calabria E, Canfora F, Adamo D Aging (Albany NY). 2023; 15(6):1708-1710.

PMID: 36934329 PMC: 10085607. DOI: 10.18632/aging.204584.

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