Evaluation of the Safety and Efficacy of a Fractional Picosecond 1064 nm Laser for Post-acne Erythema in Adult Chinese Patients

Overview

Journal Skin Res Technol

Specialty Biomedical Engineering

Date 2023 Jan 27

PMID 36704883

Authors

Ximeng Jia

Lingyu Zheng

Lin Fang

Ling Zhang

Ying Wu

Yang Yang

Yongqiang Feng

Lvping Huang

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the efficacy and safety of fractional 1064 nm picosecond Nd:YAG laser (FPNYL) in the treatment of post-acne erythema (PAE) of adult Chinese.

Materials And Methods: A total of 22 patients received 1 session of treatment and were followed up at the eighth week. Primary outcomes were measured by the Clinician erythema assessment scale (CEAS). Secondary outcomes included a global aesthetic improvement scale (GAIS) and patients' assessment of satisfaction on a five-point scale. Pain scores and adverse effects were also evaluated.

Results: Twenty-two patients with Fitzpatrick skin types III and IV were enrolled in the study and completed all treatments and follow-up visits. The mean CEAS scores fell from 2.74 ± 0.80 to 1.95 ± 0.75 (p < 0.05). The mean GAIS of PAE improvement was 2.46 ± 0.68. Erythema percentile scores by VISIA increased from 32.63 ± 7.0 to 45.75 ± 11.45 (t = 5.442, p = 0). The patient satisfaction score was 1.86 ± 1.17. The pain scores were 3.27 ± 1.17 for the FPNYL treatment (varied from 2 to 6). There were moderate erythema and oedema, which last for 3.84 ± 0.78 days. There were overall 68.18% (15/22) patients who felt pruritus in different degrees and 27.27% patients who encountered acne eruptions (white head type). No scar, hyperpigmentation or hypopigmentation was found.

Conclusion: Treatment with fractional 1064 nm picosecond Nd:YAG laser is effective and safe for PAE of Chinese patients.

Citing Articles

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Evaluation of the safety and efficacy of a fractional picosecond 1064 nm laser for post-acne erythema in adult Chinese patients.

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PMID: 36704883 PMC: 10155796. DOI: 10.1111/srt.13274.

References

Mahmoud B, Srivastava D, Janiga J, Yang J, Lim H, Ozog D . Safety and efficacy of erbium-doped yttrium aluminum garnet fractionated laser for treatment of acne scars in type IV to VI skin. Dermatol Surg. 2010; 36(5):602-9. DOI: 10.1111/j.1524-4725.2010.01513.x. View

Leight-Dunn H, Hadi A, Patel F, Yao C, Tu Y, Chapas A . The effect of a dual-wavelength 532 nm and 1064 nm picosecond-domain laser with a fractionated holographic optic on photoaging and patient age perception: A pilot study. J Cosmet Dermatol. 2021; 21(1):320-326. DOI: 10.1111/jocd.14654. View

Amiri R, Khalili M, Mohammadi S, Iranmanesh B, Aflatoonian M . Treatment protocols and efficacy of light and laser treatments in post-acne erythema. J Cosmet Dermatol. 2022; 21(2):648-656. DOI: 10.1111/jocd.14729. View

Puaratanaarunkon T, Asawanonda P . Efficacy of a one-session fractional picosecond 1064-nm laser for the treatment of atrophic acne scar and enlarged facial pores. J Cosmet Laser Ther. 2022; 23(7-8):202-206. DOI: 10.1080/14764172.2022.2055079. View

Park K, Ko E, Seo S, Hong C . Comparison of fractional, nonablative, 1550-nm laser and 595-nm pulsed dye laser for the treatment of facial erythema resulting from acne: a split-face, evaluator-blinded, randomized pilot study. J Cosmet Laser Ther. 2013; 16(3):120-3. DOI: 10.3109/14764172.2013.854626. View

Wu D, Goldman M, Wat H, Chan H . A Systematic Review of Picosecond Laser in Dermatology: Evidence and Recommendations. Lasers Surg Med. 2020; 53(1):9-49. DOI: 10.1002/lsm.23244. View

Tan A, Schlosser B, Paller A . A review of diagnosis and treatment of acne in adult female patients. Int J Womens Dermatol. 2018; 4(2):56-71. PMC: 5986265. DOI: 10.1016/j.ijwd.2017.10.006. View

Shen Y, Wang T, Zhou C, Wang X, Ding X, Tian S . Prevalence of acne vulgaris in Chinese adolescents and adults: a community-based study of 17,345 subjects in six cities. Acta Derm Venereol. 2011; 92(1):40-4. DOI: 10.2340/00015555-1164. View

Marks R . Acne and its management beyond the age of 35 years. Am J Clin Dermatol. 2005; 5(6):459-62. DOI: 10.2165/00128071-200405060-00011. View

10.

Min S, Park S, Yoon J, Kwon H, Suh D . Fractional Microneedling Radiofrequency Treatment for Acne-related Post-inflammatory Erythema. Acta Derm Venereol. 2015; 96(1):87-91. DOI: 10.2340/00015555-2164. View

11.

Perkins A, Cheng C, Hillebrand G, Miyamoto K, Kimball A . Comparison of the epidemiology of acne vulgaris among Caucasian, Asian, Continental Indian and African American women. J Eur Acad Dermatol Venereol. 2010; 25(9):1054-60. DOI: 10.1111/j.1468-3083.2010.03919.x. View

12.

Zhang M, Huang Y, Wu Q, Lin T, Gong X, Chen H . Comparison of 1064-nm and Dual-Wavelength (532/1064-nm) Picosecond-Domain Nd:YAG Lasers in the Treatment of Facial Photoaging: A Randomized Controlled Split-Face Study. Lasers Surg Med. 2021; 53(9):1158-1165. DOI: 10.1002/lsm.23404. View

13.

Zhang M, Fang J, Wu Q, Lin T . Evaluation of the Safety and Efficacy of a Picosecond Alexandrite Laser With DLA for Acne Scars in Chinese Patients. Lasers Surg Med. 2019; 52(2):176-181. DOI: 10.1002/lsm.23177. View

14.

Heng A, Chew F . Systematic review of the epidemiology of acne vulgaris. Sci Rep. 2020; 10(1):5754. PMC: 7113252. DOI: 10.1038/s41598-020-62715-3. View

15.

Jia X, Zheng L, Fang L, Zhang L, Wu Y, Yang Y . Evaluation of the safety and efficacy of a fractional picosecond 1064 nm laser for post-acne erythema in adult Chinese patients. Skin Res Technol. 2023; 29(1):e13274. PMC: 10155796. DOI: 10.1111/srt.13274. View

16.

Chang Y, Yang T, Li C . Histology changes of in vivo human skin after treatment with fractional 1064 nm Nd:YAG picosecond laser in different energy settings. Lasers Med Sci. 2021; 37(3):2087-2092. DOI: 10.1007/s10103-021-03396-w. View

17.

Guida S, Fusano M, Pellacani G, Bencini P . Fractional 1064 nm picosecond laser and skin photoaging: in vivo evaluation of treatment effects with reflectance confocal microscopy. J Cosmet Laser Ther. 2021; 23(3-4):92-96. DOI: 10.1080/14764172.2021.1994612. View

18.

Yeh Y, Peng J, Peng P . Histology of ex vivo skin after treatment with fractionated picosecond Nd:YAG laser in high and low-energy settings. J Cosmet Laser Ther. 2020; 22(1):43-47. DOI: 10.1080/14764172.2019.1710536. View

19.

Feng H, Wu Y, Jiang M, Luo X, Yan S, Lu Z . The Efficacy and Safety of Fractional 1064 nm Nd:YAG Picosecond Laser Combined With Intense Pulsed Light in the Treatment of Atrophic Acne Scar: A Split-Face Study. Lasers Surg Med. 2021; 53(10):1356-1363. DOI: 10.1002/lsm.23428. View

20.

Tan J, Liu H, Leyden J, Leoni M . Reliability of Clinician Erythema Assessment grading scale. J Am Acad Dermatol. 2014; 71(4):760-3. DOI: 10.1016/j.jaad.2014.05.044. View