Metformin Suppresses Calcium Oxalate Crystal-induced Kidney Injury by Promoting Sirt1 and M2 Macrophage-mediated Anti-inflammatory Activation

Overview

Journal Signal Transduct Target Ther

Specialties Cell Biology
Pharmacology

Date 2023 Jan 26

PMID 36702833

Authors

Haoran Liu

Chen Duan

Xiaoqi Yang

Jianhe Liu

Yaoliang Deng

Hans-Goran Tiselius

Zhangqun Ye

Tao Wang

Jinchun Xing

Hua Xu

Affiliations

Soon will be listed here.

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References

Taguchi K, Okada A, Hamamoto S, Unno R, Moritoki Y, Ando R . M1/M2-macrophage phenotypes regulate renal calcium oxalate crystal development. Sci Rep. 2016; 6:35167. PMC: 5059697. DOI: 10.1038/srep35167. View

Steiger S, Grill J, Ma Q, Bauerle T, Jordan J, Smolle M . Anti-Transforming Growth Factor β IgG Elicits a Dual Effect on Calcium Oxalate Crystallization and Progressive Nephrocalcinosis-Related Chronic Kidney Disease. Front Immunol. 2018; 9:619. PMC: 5884871. DOI: 10.3389/fimmu.2018.00619. View

Mulay S, Shi C, Ma X, Anders H . Novel Insights into Crystal-Induced Kidney Injury. Kidney Dis (Basel). 2018; 4(2):49-57. PMC: 6029228. DOI: 10.1159/000487671. View

Khan S, Pearle M, Robertson W, Gambaro G, Canales B, Doizi S . Kidney stones. Nat Rev Dis Primers. 2016; 2:16008. PMC: 5685519. DOI: 10.1038/nrdp.2016.8. View

Song A, Zhang C, Meng X . Mechanism and application of metformin in kidney diseases: An update. Biomed Pharmacother. 2021; 138:111454. DOI: 10.1016/j.biopha.2021.111454. View