Current Status and Future Perspectives of Radiomics in Hepatocellular Carcinoma

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2023 Jan 23

PMID 36683711

Authors

Joao Miranda

Natally Horvat

Gilton Marques Fonseca

Jose de Arimateia Batista Araujo-Filho

Maria Clara Fernandes

Charlotte Charbel

Jayasree Chakraborty

Fabricio Ferreira Coelho

Cesar Higa Nomura

Paulo Herman

Affiliations

Soon will be listed here.

Abstract

Given the frequent co-existence of an aggressive tumor and underlying chronic liver disease, the management of hepatocellular carcinoma (HCC) patients requires experienced multidisciplinary team discussion. Moreover, imaging plays a key role in the diagnosis, staging, restaging, and surveillance of HCC. Currently, imaging assessment of HCC entails the assessment of qualitative characteristics which are prone to inter-reader variability. Radiomics is an emerging field that extracts high-dimensional mineable quantitative features that cannot be assessed visually with the naked eye from medical imaging. The main potential applications of radiomic models in HCC are to predict histology, response to treatment, genetic signature, recurrence, and survival. Despite the encouraging results to date, there are challenges and limitations that need to be overcome before radiomics implementation in clinical practice. The purpose of this article is to review the main concepts and challenges pertaining to radiomics, and to review recent studies and potential applications of radiomics in HCC.

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