Association Analysis of and Polymorphisms and Growth Traits of Xiangsu Hybrid Pigs

Overview

Journal Genes (Basel)

Publisher MDPI

Date 2023 Jan 21

PMID 36672854

Authors

Jiali Xu

Yong Ruan

Jinkui Sun

Pengfei Shi

Jiajin Huang

Lingang Dai

Meimei Xiao

Houqiang Xu

Affiliations

Soon will be listed here.

Abstract

In this study, Xiangsu hybrid pig growth traits were evaluated via and as candidate genes. Sanger sequencing revealed three mutation sites in , namely, g.42101G>T, g.60146A>T, and g.61455G>A, and all these sites were intronic mutations. Moreover, six mutation sites were identified in : intronic g.4374G>T, exonic g.4564T>C, exonic g.6378G>A, exonic g.6386C>T, intronic g.8643G>A, and intronic g.8857A>G. Association analysis revealed that g.42101G>T, g.60146A>T, g.61455G>A, g.4374G>T, g.4564T>C, g.6378G>A, g.6386C>T, g.8643G>A, and g.8857A>G showed different relationship patterns among body weight, body length, body height, chest circumference, abdominal circumference, tube circumference, and chest depth. Real-time polymerase chain reaction results revealed that the expression of was highest in the longissimus dorsi muscle, followed by that in the heart, kidney, liver, lung, and spleen. The expression of was highest in the spleen, followed by that in the liver, kidney, lung, heart, and longissimus dorsi muscle. These results suggest that and can be used in marker-assisted selection to improve growth related traits in Xiangsu hybrid pigs, providing new candidate genes for Pig molecular breeding.

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