18F-fluorodeoxyglucose Positron Emission Tomography Findings of Peripheral Nerve Sheath Tumour of the Nasal Cavity in a Dog
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An 8-year-old Miniature Poodle presented with chronic sneezing and unilateral epistaxis. A left-sided intranasal mass was identified on computed tomography. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) was performed to evaluate the metabolic activity of the mass. The intranasal mass showed mildly increased 18F-FDG uptake. The maximal and mean standardized uptake values (SUVs) of the mass were 3.4 and 2.6, respectively. The maximal SUV of the mass/mean SUV of the normal liver was 2.5. The 7-cm soft, pink mass was easily removed through rhinoscopy, with subsequent dramatic improvement in clinical signs. Histopathological and immunohistochemical analyses determined that the mass was an intermediate-grade malignant peripheral nerve sheath tumour (PNST). This is the first report of 18F-FDG PET findings in a PNST in dogs.
Lee D, Yun H, Yun T, Koo Y, Chae Y, Nam H Vet Med Sci. 2023; 9(2):584-590.
PMID: 36626300 PMC: 10029900. DOI: 10.1002/vms3.1069.