Normal Reference Values of Tricuspid Annular Dimensions and Functional Properties in Healthy Adults Using Three-dimensional Speckle-tracking Echocardiography (insights from the MAGYAR-Healthy Study)

Overview

Journal Quant Imaging Med Surg

Specialty Radiology

Date 2023 Jan 9

PMID 36620137

Authors

Attila Nemes

Arpad Kormanyos

Gergely Racz

Zoltan Ruzsa

Nora Ambrus

Csaba Lengyel

Affiliations

Soon will be listed here.

Abstract

Background: Three-dimensional speckle-tracking echocardiography (3DSTE) is a relatively new non-invasive imaging modality with ability for simultaneous chamber quantifications and determination of valvular dimensions. The aim of the present retrospective cohort study was to determine normal reference values of 3DSTE-derived tricuspid annular (TA) dimensions and functional properties and to evaluate their age- and gender dependency.

Methods: The present study comprised 156 healthy adult subjects, from which 28 cases were excluded due to inferior image quality, therefore the remaining group consisted of 128 cases with the mean age of 35.4±12.5 years (72 males). The subject population was further divided into the following categories: 18-29 years (n=57; mean age: 25.2±2.8 years, 51 males), 30-39 years (n=29; mean age: 34.1±2.5 years, 31 males), 40-49 years (n=17; mean age: 44.1±3.2 years, 11 males) and ≥50 years of age (n=25, mean age: 59.2±6.4 years, 14 males).

Results: End-diastolic TA diameter (2.2±0.3 2.5±0.3 cm, P<0.05), area (7.1±1.3 8.1±1.7 cm, P<0.05) and perimeter (10.3±0.9 11.0±1.2 cm, P<0.05) were lower in females than in males in the 18-29 year-old group and TA area (6.1±0.8 8.0±1.2 cm, P<0.05) and TA perimeter (9.7±0.8 11.0±0.9 cm, P<0.05) were lower in females than in males in the 40-49 year-old group. End-systolic TA diameter were lower in females than in males in the 18-29 year-old group (1.8±0.2 1.9±0.3 cm, P<0.05) and TA area (4.7±0.3 6.3±1.2 cm, P<0.05) and TA perimeter (8.6±0.4 9.5±0.9 cm, P<0.05) were lower in females than in males in the 40-49 year-old group. TA fractional area change was found to be reduced in the 40-49 year-old group as compared to the 30-39 year-old group (21.7%±8.7% 29.2%±10.0%, P<0.05).

Conclusions: 3DSTE is a novel method for non-invasive assessment of TA dimensions and functional properties. Results highlight the importance of age- and gender-specific reference values in case of TA diameter, area and perimeter and calculated functional features respecting the cardiac cycle.

Citing Articles

Comparison of dimensions and functional features of mitral and tricuspid annuli in the same healthy adults: insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study.

Nemes A, Kormanyos A, Lengyel C Quant Imaging Med Surg. 2024; 14(9):6780-6791.

PMID: 39281171 PMC: 11400638. DOI: 10.21037/qims-24-630.

Mitral and Tricuspid Annular Abnormalities in Hypereosinophilic Syndrome-Insights from the Three-Dimensional Speckle-Tracking Echocardiographic MAGYAR-Path Study.

Nemes A, Kormanyos A, Racz G, Ambrus N, Marton I, Borbenyi Z Rev Cardiovasc Med. 2024; 24(4):115.

PMID: 39076275 PMC: 11273037. DOI: 10.31083/j.rcm2404115.

Three-Dimensional Speckle-Tracking Echocardiography-Derived Tricuspid Annular Properties in Acromegaly-Results from the MAGYAR-Path Study.

Nemes A, Racz G, Kormanyos A, Gyenes N, Ambrus N, Lengyel C Biomedicines. 2024; 12(7).

PMID: 39062037 PMC: 11274697. DOI: 10.3390/biomedicines12071464.

The Relationship between Tricuspid Annular Longitudinal and Sphincter-like Features of Its Function in Healthy Adults: Insights from the MAGYAR-Healthy Study.

Nemes A, Racz G, Kormanyos A, Ruzsa Z, Achim A, Lengyel C Life (Basel). 2023; 13(10).

PMID: 37895460 PMC: 10608609. DOI: 10.3390/life13102079.

Tricuspid annular and right atrial volume changes are associated in healthy adults-insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study.

Nemes A, Kormanyos A, Racz G, Ruzsa Z, Achim A, Ambrus N Front Cardiovasc Med. 2023; 10:1140599.

PMID: 37731528 PMC: 10507328. DOI: 10.3389/fcvm.2023.1140599.

References

Ricci F, Aung N, Gallina S, Zemrak F, Fung K, Bisaccia G . Cardiovascular magnetic resonance reference values of mitral and tricuspid annular dimensions: the UK Biobank cohort. J Cardiovasc Magn Reson. 2021; 23(1):5. PMC: 7788733. DOI: 10.1186/s12968-020-00688-y. View

Amini Khoiy K, Asgarian K, Loth F, Amini R . Dilation of tricuspid valve annulus immediately after rupture of chordae tendineae in ex-vivo porcine hearts. PLoS One. 2018; 13(11):e0206744. PMC: 6226105. DOI: 10.1371/journal.pone.0206744. View

Kormanyos A, Kalapos A, Domsik P, Gyenes N, Lengyel C, Nemes A . Normal reference values of left ventricular volumetric parameters in healthy adults-real-life single-center experience from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study. Quant Imaging Med Surg. 2021; 11(4):1496-1503. PMC: 7930697. DOI: 10.21037/qims-20-786. View

Nemes A, Kovacs Z, Kormanyos A, Domsik P, Kalapos A, Piros G . The mitral annulus in lipedema: Insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study. Echocardiography. 2019; 36(8):1482-1491. DOI: 10.1111/echo.14429. View

Kaemmerer A, Gorenflo M, Huscher D, Pittrow D, Ewert P, Pausch C . Medical treatment of pulmonary hypertension in adults with congenital heart disease: updated and extended results from the International COMPERA-CHD Registry. Cardiovasc Diagn Ther. 2022; 11(6):1255-1268. PMC: 8748472. DOI: 10.21037/cdt-21-351. View

Nemes A, Kormanyos A, Kalapos A, Domsik P, Gyenes N, Ambrus N . Normal reference values of left ventricular strain parameters in healthy adults: Real-life experience from the single-center three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study. J Clin Ultrasound. 2020; 49(4):368-377. DOI: 10.1002/jcu.22940. View

Dwivedi G, Mahadevan G, Jimenez D, Frenneaux M, Steeds R . Reference values for mitral and tricuspid annular dimensions using two-dimensional echocardiography. Echo Res Pract. 2015; 1(2):43-50. PMC: 4676479. DOI: 10.1530/ERP-14-0050. View

Nemes A, Kormanyos A, Domsik P, Kalapos A, Gyenes N, Lengyel C . Normal reference values of three-dimensional speckle-tracking echocardiography-derived mitral annular dimensions and functional properties in healthy adults: Insights from the MAGYAR-Healthy Study. J Clin Ultrasound. 2020; 49(3):234-239. DOI: 10.1002/jcu.22875. View

Nemes A, Kormanyos A, Domsik P, Kalapos A, Lengyel C, Forster T . Normal reference values of three-dimensional speckle-tracking echocardiography-derived left atrial strain parameters (results from the MAGYAR-Healthy Study). Int J Cardiovasc Imaging. 2019; 35(6):991-998. PMC: 6534516. DOI: 10.1007/s10554-019-01559-z. View

10.

Kormanyos A, Kalapos A, Domsik P, Lengyel C, Forster T, Nemes A . Normal values of left ventricular rotational parameters in healthy adults-Insights from the three-dimensional speckle tracking echocardiographic MAGYAR-Healthy Study. Echocardiography. 2019; 36(4):714-721. DOI: 10.1111/echo.14285. View

11.

Nemes A, Kormanyos A, Domsik P, Kalapos A, Ambrus N, Lengyel C . Normal reference values of three-dimensional speckle-tracking echocardiography-derived right atrial volumes and volume-based functional properties in healthy adults (Insights from the MAGYAR-Healthy Study). J Clin Ultrasound. 2019; 48(5):263-268. DOI: 10.1002/jcu.22795. View

12.

Anwar A, Geleijnse M, Soliman O, McGhie J, Frowijn R, Nemes A . Assessment of normal tricuspid valve anatomy in adults by real-time three-dimensional echocardiography. Int J Cardiovasc Imaging. 2007; 23(6):717-24. PMC: 2048827. DOI: 10.1007/s10554-007-9210-3. View

13.

Nemes A, Kalapos A, Domsik P, Forster T . [Three-dimensional speckle-tracking echocardiography -- a further step in non-invasive three-dimensional cardiac imaging]. Orv Hetil. 2012; 153(40):1570-7. DOI: 10.1556/OH.2012.29466. View

14.

Nemes A, Racz G, Kormanyos A, Ambrus N, Havasi K . Tricuspid annular abnormalities following different surgical strategies in adults with corrected tetralogy of Fallot (Results from the CSONGRAD Registry and MAGYAR-Path Study). Cardiovasc Diagn Ther. 2022; 11(6):1276-1283. PMC: 8748490. DOI: 10.21037/cdt-21-256. View

15.

Anwar A, Soliman O, Nemes A, van Geuns R, Geleijnse M, Ten Cate F . Value of assessment of tricuspid annulus: real-time three-dimensional echocardiography and magnetic resonance imaging. Int J Cardiovasc Imaging. 2007; 23(6):701-5. PMC: 2048828. DOI: 10.1007/s10554-006-9206-4. View

16.

Putthapiban P, Amini M, Abudayyeh I . Anatomy of the Tricuspid Valve and Pathophysiology of Tricuspid Regurgitation. Interv Cardiol Clin. 2021; 11(1):1-9. DOI: 10.1016/j.iccl.2021.09.003. View

17.

Urbano-Moral J, Patel A, Maron M, Arias-Godinez J, Pandian N . Three-dimensional speckle-tracking echocardiography: methodological aspects and clinical potential. Echocardiography. 2012; 29(8):997-1010. DOI: 10.1111/j.1540-8175.2012.01773.x. View

18.

Lang R, Badano L, Mor-Avi V, Afilalo J, Armstrong A, Ernande L . Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2015; 16(3):233-70. DOI: 10.1093/ehjci/jev014. View

19.

Nemes A, Kormanyos A, Domsik P, Kalapos A, Ambrus N, Lengyel C . Normal reference values of left atrial volumes and volume-based functional properties using three-dimensional speckle-tracking echocardiography in healthy adults (Insights from the MAGYAR-Healthy Study). J Clin Ultrasound. 2020; 49(1):49-55. DOI: 10.1002/jcu.22879. View

20.

Nemes A, Kormanyos A, Domsik P, Kalapos A, Ambrus N, Lengyel C . Normal reference values of right atrial strain parameters using three-dimensional speckle-tracking echocardiography (results from the MAGYAR-Healthy Study). Int J Cardiovasc Imaging. 2019; 35(11):2009-2018. PMC: 6805961. DOI: 10.1007/s10554-019-01655-0. View