Evaluation of the Effectiveness of the Modified Nutrition Risk in the Critically Ill (mNUTRIC) Score in Critically Ill Patients Affected by COVID-19 Admitted to the Intensive Care Unit (ICU)

Overview

Journal BMC Nutr

Publisher Biomed Central

Specialty Nutritional Sciences

Date 2022 Dec 30

PMID 36585718

Authors

Babak Alikiaii

Seyed Taghi Hashemi

Zahra Kiani

Zahra Heidari

Behzad Nazemroaya

Mohammad Golparvar

Somayyeh Daneshmanesh

Shirin Fattahpour

Sepide Amini

Mehrnaz Shojaei

Mohammad Bagherniya

Affiliations

Soon will be listed here.

Abstract

Background: COVID-19 is a very harmful pandemic, and its recovery process is highly influenced by nutritional status; however, an appropriate nutritional scale has not yet been proposed for these patients. Therefore, the purpose of this study was to evaluate the effectiveness of the modified Nutrition Risk in the Critically ill (mNUTRIC) score in critically ill patients affected by COVID-19 admitted to the intensive care unit (ICU).

Material And Methods: This was a cross-sectional study performed on 204 critically ill patients affected by COVID-19 admitted to the ICU wards. Evaluated indicators include the mNUTRIC Score as well as demographic, and biochemical indicators.

Results: A high percentage of COVID-19 patients (67.2%) had severe disease. Hospital and ICU stay (p > 0.001) and PH (p > 0.001) values were significantly lower in non-survivors than in survivors. mNUTRIC score (p > 0.001), PCO2 (p = 0.003), and CRP levels (p = 0.021) were significantly higher in non-survivors than survivors. mNUTRIC score had a direct correlation with age (p > 0.001), AST (p = 0.000), LDH (p = 0.026), and CRP (p = 0.014) and an inverse correlation with hospital duration (p = 0.031), albumin (p = 0.003) and PH (p < 0.001). Furthermore, there was a non-significant correlation between the mNUTRIC score and mortality chance (OR = 1.085, 95%CI [0.83, 1.42], p = 0.552). While, patients with more severe COVID-19 disease (OR = 8.057, 95%CI [1.33, 48.64], p = 0.023) and higher PCO2 (OR = 1.042, 95%CI [1.01, 1.08], p = 0.023) levels had higher odds of mortality.

Conclusions: Our findings revealed that COVID-19 patients with higher CRP levels and lower PH had higher mortality and poor nutritional condition. Moreover, there was a non-significant association between the mNUTRIC score and mortality chance.

Citing Articles

Effect of the modified NUTRIC score in predicting the prognosis of patients admitted to intensive care units.

Yildirim M, Yildirim Z, Deniz M BMC Anesthesiol. 2024; 24(1):473.

PMID: 39716089 PMC: 11664814. DOI: 10.1186/s12871-024-02866-2.

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