Association of Different ABO and Rh Blood Groups with the Erythroprotective Effect of Extracts from and Their Anti-Inflammatory and Antiproliferative Properties

Overview

Journal Metabolites

Publisher MDPI

Date 2022 Dec 23

PMID 36557241

Authors

Saul Ruiz-Cruz

Ricardo Ivan Gonzalez-Vega

Ramon Enrique Robles-Zepeda

Aline Reyes-Diaz

Jose Antonio Lopez-Elias

Maritza Lizeth Alvarez-Ainza

Francisco Javier Cinco-Moroyoqui

Ramon Alfonso Moreno-Corral

Francisco Javier Wong-Corral

Jesus Borboa-Flores

Yaeel Isbeth Cornejo-Ramirez

Carmen Lizette Del-Toro-Sanchez

Affiliations

Soon will be listed here.

Abstract

Previous studies have reported that different blood groups are associated with the risk of chronic degenerative diseases that mainly involve inflammation and neoplastic processes. We investigate the relationship between blood groups and the erythroprotective effect of extracts from against oxidative damage as a proposal to develop drugs designed for people with a specific blood type related to chronic pathology. The study was carried out through the elucidation of the erythroprotective potential, anti-inflammatory and antiproliferative activity of . Research suggests that the presence or absence of certain blood groups increases or decreases the abilities of certain phytochemicals to inhibit oxidative stress, which is related to the systemic inflammatory response involved in the development of different types of cancer. The pigment-rich extracts from inhibit ROO•- induced oxidative stress in human erythrocytes on the A RhD+ve antigen without compromising the structure of the cell membrane. This result is very important, since the A antigen is related to the susceptibility of contracting prostate cancer. Similarly, it was possible to inhibit the proliferation of cervical (HeLa) and prostate (PC-3) carcinoma. The combinatorial analysis of different biological activities can help design phytochemicals as new candidates for preventive drugs treating the chronic degenerative diseases associated with a specific blood group.

Citing Articles

Impact of the ABO and RhD Blood Groups on the Evaluation of the Erythroprotective Potential of Fucoxanthin, β-Carotene, Gallic Acid, Quercetin and Ascorbic Acid as Therapeutic Agents against Oxidative Stress.

Gonzalez-Vega R, Robles-Garcia M, Mendoza-Urizabel L, Cardenas-Enriquez K, Ruiz-Cruz S, Gutierrez-Lomeli M Antioxidants (Basel). 2023; 12(12).

PMID: 38136212 PMC: 10740450. DOI: 10.3390/antiox12122092.

Erythroprotective Potential of Phycobiliproteins Extracted from .

Pena-Medina R, Fimbres-Olivarria D, Enriquez-Ocana L, Martinez-Cordova L, Del-Toro-Sanchez C, Lopez-Elias J Metabolites. 2023; 13(3).

PMID: 36984806 PMC: 10057957. DOI: 10.3390/metabo13030366.

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